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Somavert
Pegvisomant
$11145.00
10MG · 3 × 30 pre-filled syringe · 3 months supply
BrandBranded medicine· By Pfizer
$3715.00 per month
Strength
How long a supply?
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Ships cold, in insulated packing
This medicine ships in insulated packing with coolant and carries its own shipping charge, shown at checkout.
Annual cost
$44580a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
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About Somavert
Overview
Somavert contains pegvisomant, a medicine used to treat acromegaly when surgery or radiation therapy has not worked well enough or is not appropriate. It blocks growth hormone from attaching to its receptors on cells, lowering blood levels of insulin-like growth factor-1 (IGF-1). The goal of treatment is to bring IGF-1 levels into the normal range.
What it treats
Acromegaly in patients who have not responded adequately to surgery or radiation therapy, or for whom these treatments are not appropriate. The treatment goal is to bring blood insulin-like growth factor-1 (IGF-1) levels into the normal range.
Safety information
Side effects
Commonly reported side effects include infection, pain, nausea, diarrhea, abnormal liver test results, flu-like symptoms and injection-site reactions. Serious side effects that warrant contacting a doctor include low blood sugar in people with diabetes, liver toxicity and allergic reactions affecting the whole body. Blood glucose should be monitored in people with diabetes, and their diabetes medicines may need adjustment by their doctor. Liver toxicity may require more frequent liver tests or stopping Somavert under medical supervision. A buildup of fatty tissue at injection sites can also occur.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
The supplied FDA label lists no contraindications for Somavert (pegvisomant). Conditions requiring caution include: • Diabetes: Blood glucose should be monitored because low blood sugar may occur. Your prescriber may need to reduce your diabetes medicines. • Liver toxicity: More frequent liver tests and/or stopping Somavert may be needed. • Systemic hypersensitivity (an allergic reaction affecting the body): Close monitoring is needed when restarting Somavert in patients who have experienced this. • Premenopausal women should be advised of the potential for an unintended pregnancy.
Interactions
Tell your doctor if you use insulin, oral medicines for diabetes or opioids. If you have acromegaly and diabetes, careful monitoring may be needed, and your doctor may need to reduce your diabetes medicine. Opioid use may affect how much Somavert is needed to adequately lower IGF-1 levels; your prescriber will decide whether an adjustment is needed.
Using Somavert
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label SOMAVERT (PEGVISOMANT) KIT [PHARMACIA & UPJOHN COMPANY LLC] (DailyMed, retrieved 19 September 2026).
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