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Galafold
Migalastat Hydrochloride
$102195.00
123mg · 3 × 14 tablets · 3 months supply
BrandBranded medicine· By Amicus Therapeutics
$34065.00 per month
How long a supply?
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Annual cost
$442845a year at this pack size
Prescription required
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About Galafold
Overview
Galafold contains migalastat, present as migalastat hydrochloride, and is used to treat adults with confirmed Fabry disease who have a GLA gene variant considered amenable to treatment based on laboratory testing. It works by stabilising an enzyme called alpha-galactosidase A, helping it reach the parts of cells where it breaks down certain fatty substances. Galafold received accelerated FDA approval based on reduced GL-3 accumulation in certain kidney cells; continued approval may depend on confirmatory trials verifying clinical benefit.
What it treats
Fabry disease in adults with a confirmed diagnosis and a GLA gene variant shown by laboratory testing to be amenable to treatment with Galafold.
Safety information
Side effects
Common side effects include headache, inflammation of the nose and throat, urinary tract infection, nausea and fever. These were reported in at least 10% of patients.
Before taking this medicine
The FDA label lists no contraindications for Galafold.
Interactions
For information about clinically significant drug interactions, ask your doctor to review the full prescribing information.
Using Galafold
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label GALAFOLD (MIGALASTAT HYDROCHLORIDE) CAPSULE [AMICUS THERAPEUTICS US, LLC] (DailyMed, retrieved 19 September 2026).
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