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VYVGART Hytrulo
Efgartigimod Alfa And Hyaluronidase‑qvfc
$16070.00
40mg/20ml · 1 vial
BrandBranded medicine· By argenx
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40mg/20ml
180mg/ml
About VYVGART Hytrulo
Overview
VYVGART Hytrulo contains efgartigimod alfa and hyaluronidase-qvfc and is given as an injection under the skin. It is used to treat adults with generalized myasthenia gravis (gMG) or chronic inflammatory demyelinating polyneuropathy (CIDP). Efgartigimod alfa lowers the amount of immunoglobulin G (IgG) antibodies circulating in the blood, while hyaluronidase helps the medicine spread and be absorbed under the skin.
What it treats
Generalized myasthenia gravis (gMG) in adults. Chronic inflammatory demyelinating polyneuropathy (CIDP) in adults.
Safety information
Side effects
Common side effects include injection-site reactions. Respiratory tract infections, headache and urinary tract infections were also common in patients with gMG treated with efgartigimod alfa-fcab. Serious infections, allergic reactions and injection-related reactions can occur. Contact your doctor if you develop signs or symptoms of infection; treatment may need to be delayed or withheld until the infection resolves. Seek urgent medical attention for a severe allergic or injection-related reaction. Reported allergic reactions include anaphylaxis, low blood pressure causing fainting, swelling (angioedema), difficulty breathing, rash and hives.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use VYVGART Hytrulo if you have had a serious allergic reaction to efgartigimod alfa products, hyaluronidase or any other ingredient in this medicine. Reactions have included anaphylaxis and low blood pressure leading to fainting. Treatment should be delayed if you have an active infection. You should be monitored for signs of infection during treatment. If a serious infection develops, it should be treated, and your healthcare professional may withhold VYVGART Hytrulo until it has resolved. Seek medical attention if you develop an allergic reaction, such as swelling, difficulty breathing, rash, hives or fainting. Injection-related reactions also require assessment. After a severe reaction, your healthcare professional should weigh the risks and benefits before giving the medicine again. After a mild or moderate reaction, further treatment may require close observation and other precautions.
Interactions
VYVGART Hytrulo may reduce the effectiveness of medicines that bind to the human neonatal Fc receptor (FcRn). Tell your doctor about your other medicines so they can check for this interaction and closely monitor their effectiveness. If long-term use of an affected medicine is essential, your doctor may consider stopping VYVGART Hytrulo and using an alternative treatment.
Using VYVGART Hytrulo
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label VYVGART HYTRULO (EFGARTIGIMOD ALFA AND HYALURONIDASE (HUMAN RECOMBINANT)) INJECTION, SOLUTION [ARGENX US] (DailyMed, retrieved 19 September 2026).
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