Firazyr, illustration of pre-filled syringe form (not a photo of the actual pack)

Illustrative image.

Firazyr

Icatibant (as Acetate)

Prescription required

$3070.00

30MG/3ML · 1 pre-filled syringe

BrandBranded medicine· By Takeda

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About Firazyr

Overview

Firazyr contains icatibant (as acetate) and is supplied in a pre-filled syringe. It is used to treat acute attacks of hereditary angioedema (HAE) in adults aged 18 years and older. It works by blocking the action of bradykinin, a substance thought to cause the swelling, inflammation and pain associated with HAE attacks.

What it treats

Acute attacks of hereditary angioedema (HAE) in adults aged 18 years and older.

Safety information

Side effects

The most common side effects are injection site reactions, reported in 97% of patients in clinical trials. Other common side effects include fever, increased liver enzymes (transaminases), dizziness and rash. The label also warns that attacks affecting the throat (laryngeal attacks) require immediate medical attention, even after treatment with Firazyr. This is a warning about the attack, not a side effect of the medicine.

When to call your doctor

• Seek immediate medical attention for an attack affecting your throat (larynx), even after treatment with Firazyr.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

The label lists no contraindications for Firazyr. If it is used to treat an attack affecting the larynx (voice box), seek immediate medical attention after treatment. Older adults have higher exposure to icatibant, but no differences in safety or effectiveness have been identified compared with younger patients.

Using Firazyr

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label FIRAZYR (ICATIBANT ACETATE) INJECTION, SOLUTION [TAKEDA PHARMACEUTICALS AMERICA, INC.] (DailyMed, retrieved 19 September 2026).

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