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Vidaza
Azacitidine
$774.00
100mg · 100 vial
BrandBranded medicine· By Celgene
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About Vidaza
Overview
Vidaza contains azacitidine and is supplied as a powder in a vial for injection. It treats adults with certain types of myelodysplastic syndromes (MDS), including chronic myelomonocytic leukemia (CMMoL). It also treats newly diagnosed juvenile myelomonocytic leukemia (JMML) in children aged 1 month and older. It is thought to work by reducing chemical marks on DNA that affect gene activity and by killing abnormal, rapidly dividing cells in the bone marrow.
What it treats
- Certain myelodysplastic syndrome (MDS) subtypes in adults: refractory anemia or refractory anemia with ringed sideroblasts when accompanied by low neutrophil or platelet counts, or when transfusions are required; refractory anemia with excess blasts; refractory anemia with excess blasts in transformation; and chronic myelomonocytic leukemia. - Newly diagnosed juvenile myelomonocytic leukemia (JMML) in children aged 1 month and older.
Safety information
Side effects
Common side effects in adults with myelodysplastic syndromes (MDS) include nausea, vomiting, diarrhea, constipation, fever, redness at the injection site, bruising, and low red blood cell, white blood cell or platelet counts. With intravenous treatment, common side effects also include small red or purple spots on the skin, chills, weakness and low potassium levels. In children with juvenile myelomonocytic leukemia (JMML), common side effects include fever, rash, upper respiratory tract infections and low red blood cell counts. Serious side effects that warrant contacting a doctor include low blood cell counts, liver toxicity, kidney toxicity and tumor lysis syndrome, which can be fatal. Frequent blood count checks are needed. People with severe existing liver problems have a higher risk of toxicity, and those with kidney problems need monitoring. Tumor lysis syndrome requires risk assessment and monitoring. Vidaza can harm an unborn baby. Female patients who could become pregnant and male patients whose partners could become pregnant should use effective contraception. Contact your doctor if pregnancy occurs or is suspected during treatment.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Vidaza must not be used in people with advanced malignant liver tumors or an allergy to azacitidine or mannitol. Caution and monitoring are needed in people with severe pre-existing liver impairment or kidney impairment because of an increased risk of toxicity. Vidaza can cause low red blood cell, white blood cell and platelet counts, so complete blood counts must be checked frequently. It can also cause serious or fatal tumor lysis syndrome, a complication of cancer cell breakdown; risk assessment and monitoring are needed. Vidaza can harm an unborn baby. Female patients who could become pregnant, and male patients with female partners who could become pregnant, should use effective contraception. Do not breastfeed during treatment.
Using Vidaza
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label VIDAZA (AZACITIDINE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [CELGENE CORPORATION] (DailyMed, retrieved 19 September 2026).
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