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Myfortic
Mycophenolic Acid
$549.00
180mg · 3 × 120 tablets · 6 months supply
BrandBranded medicine· By Novartis
$91.50 per month
Strength
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Annual cost
$1098a year at this pack size
Prescription required
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180mg
360mg
FDA boxed warningEmbryo-fetal toxicity, malignancies, and serious infections
Use during pregnancy is associated with increased risks of pregnancy loss and congenital malformations. Avoid if safer treatment options are available.
Females of reproductive potential must be counseled regarding pregnancy prevention and planning.
Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe mycophenolic acid delayed-release tablets.
Increased risk of development of lymphoma and other malignancies, particularly of the skin, due to immunosuppression.
Increased susceptibility to bacterial, viral, fungal, and protozoal infections, including opportunistic infections.
About Myfortic
Overview
Myfortic is a prescription immunosuppressant containing mycophenolic acid in delayed-release tablets. It is used to help prevent kidney transplant rejection in adults and in children aged 5 years and older who are at least 6 months past their kidney transplant. It is used in combination with cyclosporine and corticosteroids. It works by blocking a process that certain immune cells need to multiply, reducing the immune response against the transplanted kidney.
What it treats
- Prevention of organ rejection in adults receiving a kidney transplant. - Prevention of organ rejection in children aged 5 years and older who are at least 6 months past a kidney transplant. Used in combination with cyclosporine and corticosteroids.
Safety information
Side effects
Common side effects include low red blood cell counts (anemia), low white blood cell counts, constipation, nausea, diarrhea, vomiting, indigestion, urinary tract infections, cytomegalovirus (CMV) infection, difficulty sleeping and pain after surgery. Serious side effects that warrant contacting a doctor include: • Serious infections, including new or reactivated viral infections. These can be life-threatening or fatal and may damage the kidneys or cause loss of the transplanted kidney. • New weakness on one side of the body, confusion, changes in thinking or difficulty with coordination. These may be signs of progressive multifocal leukoencephalopathy (PML), a serious brain infection that can be fatal. • Blood disorders, including severe reductions in white or red blood cells and pure red cell aplasia, a condition in which the body does not make enough red blood cells. Regular blood tests are needed to monitor for these problems. • Bleeding, ulcers or holes in the stomach or intestines. • Fever with joint pain, joint swelling or muscle pain. These may be signs of an acute inflammatory syndrome that has sometimes required hospital treatment. • Severe allergic reactions, including angioedema (swelling) and anaphylaxis. Seek emergency medical help if a severe allergic reaction occurs. Mycophenolic acid also increases the risk of lymphoma and other cancers, particularly skin cancer. Limit sunlight and UV exposure, wear protective clothing and use a broad-spectrum sunscreen with a high protection factor. Use during pregnancy increases the risk of miscarriage in the first trimester and serious birth defects. Contact your doctor promptly if you become pregnant or are planning a pregnancy.
FDA boxed warning
Embryo-fetal toxicity, malignancies, and serious infections
Use during pregnancy is associated with increased risks of pregnancy loss and congenital malformations. Avoid if safer treatment options are available.
Females of reproductive potential must be counseled regarding pregnancy prevention and planning.
Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe mycophenolic acid delayed-release tablets.
Increased risk of development of lymphoma and other malignancies, particularly of the skin, due to immunosuppression.
Increased susceptibility to bacterial, viral, fungal, and protozoal infections, including opportunistic infections.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Myfortic if you have had an allergic reaction, including anaphylaxis, to mycophenolate sodium, mycophenolic acid, mycophenolate mofetil or any tablet ingredient. Avoid use in people with rare inherited HGPRT deficiency, such as Lesch-Nyhan or Kelley-Seegmiller syndrome, because it may worsen these conditions. Myfortic increases the risk of miscarriage and birth defects. Avoid use during pregnancy if safer treatment options are available. Women who could become pregnant need counselling about pregnancy prevention and planning. Sexually active men and/or their female partners should use effective contraception during treatment and for at least 90 days after treatment ends. Treatment requires supervision by a doctor experienced in immunosuppression and transplant care. Particular caution and monitoring are needed in people with serious active digestive system disease, low white blood cell counts or anaemia, or infections, including hepatitis B or C. Serious infections, gastrointestinal bleeding, ulcers and intestinal perforation can occur. Regular blood tests are needed. Immunosuppression increases the risk of lymphoma and other cancers, particularly skin cancer. Limit sunlight and UV exposure with protective clothing and a broad-spectrum sunscreen with a high protection factor. Severe allergic reactions and an inflammatory syndrome involving fever, joint pain or muscle pain have also been reported. Avoid live vaccines during treatment and discuss any vaccination with your doctor; vaccines may be less effective. Do not donate blood during treatment or for at least 6 weeks afterwards, or semen during treatment or for 90 days afterwards.
Interactions
Myfortic (mycophenolic acid) can interact with the following medicines: • Antacids containing magnesium and aluminum hydroxides, sevelamer and other calcium-free phosphate binders should not be taken at the same time as Myfortic because they may lower mycophenolic acid levels. • Azathioprine and mycophenolate mofetil (MMF) are not recommended for use alongside Myfortic. • Cholestyramine, other bile acid binders and oral activated charcoal should not be used with Myfortic because they may lower mycophenolic acid levels and reduce its effectiveness. • Cyclosporine may lower mycophenolic acid levels. Switching to or from cyclosporine requires care because these levels may change. • Norfloxacin and metronidazole used together may lower mycophenolic acid levels; this combination is not recommended with Myfortic. The label reports no such effect when either antibiotic is used separately. • Rifampin may lower mycophenolic acid levels and is not recommended with Myfortic unless the benefit outweighs the risk. • Hormonal contraceptives may be less effective. An additional barrier contraceptive method must be used with hormonal contraception, including the pill, patch, vaginal ring, injection or implant. • Acyclovir, valacyclovir, ganciclovir and valganciclovir may increase levels of both the antiviral medicine and a breakdown product of mycophenolic acid, especially in people with reduced kidney function. Blood cell counts should be monitored during combined treatment. Other medicines cleared through the same kidney pathway may also interact. • Ciprofloxacin and amoxicillin with clavulanic acid may reduce the amount of mycophenolic acid available for absorption by changing gut bacteria. The clinical importance of this interaction is unclear. Pantoprazole did not change mycophenolic acid exposure in the study described in the label.
Using Myfortic
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label MYCOPHENOLIC ACID TABLET, DELAYED RELEASE [STELLON BIOTECH INC.] (DailyMed, retrieved 19 September 2026).
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