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Ilaris
Canakinumab
$70050.00
150mg/ml · 3 × 1 bottle · 3 months supply
BrandBranded medicine· By Novartis
$23350.00 per month
How long a supply?
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Annual cost
$280200a year at this pack size
Prescription required
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About Ilaris
Overview
Ilaris (canakinumab) is a prescription medicine used to treat periodic fever syndromes, including cryopyrin-associated periodic syndromes (CAPS) in adults and children aged 4 years and older, and TRAPS, hyperimmunoglobulin D syndrome/mevalonate kinase deficiency (HIDS/MKD), and familial Mediterranean fever (FMF) in adults and children. It also treats active Still’s disease, including adult-onset Still’s disease and systemic juvenile idiopathic arthritis, in patients aged 2 years and older. In adults, it treats gout flares when NSAIDs and colchicine cannot be used, are not tolerated or do not work well enough, and repeated courses of corticosteroids are not appropriate. It works by blocking interleukin-1 beta (IL-1β), a protein that drives inflammation.
What it treats
- Cryopyrin-associated periodic syndromes (CAPS), including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS), in adults and children aged 4 years and older. - Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in adults and children. - Hyperimmunoglobulin D syndrome (HIDS)/mevalonate kinase deficiency (MKD) in adults and children. - Familial Mediterranean fever (FMF) in adults and children. - Active Still’s disease, including adult-onset Still’s disease and systemic juvenile idiopathic arthritis, in patients aged 2 years and older. - Gout flares in adults when NSAIDs and colchicine cannot be used, are not tolerated or do not work adequately, and repeated courses of corticosteroids are not appropriate.
Safety information
Side effects
Common side effects vary by the condition being treated: • CAPS: nose and throat infections, diarrhea, flu, runny nose, nausea, headache, bronchitis, stomach and intestinal infections, sore throat, weight gain, muscle and joint pain, and a spinning sensation (vertigo). • TRAPS, HIDS/MKD and FMF: injection-site reactions and nose and throat infections. • Still’s disease: nose and throat or upper respiratory tract infections, abdominal pain and injection-site reactions. • Gout flares: nose and throat or upper respiratory tract infections, urinary tract infections, raised blood triglycerides and back pain. Serious risks include serious infections, suppression of the immune system, hypersensitivity reactions and macrophage activation syndrome. A serious drug reaction called DRESS (drug reaction with eosinophilia and systemic symptoms) can also occur. Contact a doctor promptly if you develop an infection or suspect a serious reaction. ILARIS must be stopped if a serious infection or hypersensitivity reaction develops; hypersensitivity reactions require prompt treatment and monitoring until they resolve.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Ilaris if you have a confirmed allergy to canakinumab or any of its other ingredients. Ilaris should not be given during an active infection that requires medical treatment. Ilaris has been associated with an increased risk of serious infections. Tell your prescriber if you have an infection, a history of recurring infections, or a condition that makes you more likely to develop infections. Ilaris must be stopped if a serious infection develops. Allergic reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS), can occur. If a reaction occurs, Ilaris must be stopped, prompt treatment is needed, and monitoring should continue until the reaction resolves. Avoid live vaccines during treatment. Recommended vaccinations should be updated before starting Ilaris.
Interactions
Formal studies of interactions between Ilaris (canakinumab) and other medicines have not been conducted.
Using Ilaris
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place with the bottle tightly closed, away from direct light and moisture. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ILARIS (CANAKINUMAB) INJECTION, SOLUTION [NOVARTIS PHARMACEUTICALS CORPORATION] (DailyMed, retrieved 19 September 2026).
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