HyperHEP B, illustration of pre-filled syringe form (not a photo of the actual pack)

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HyperHEP B

Hepatitis B Immune Globulin (human)

Prescription required

$2890.00

500IU · 5

BrandBranded medicine· By Biotest

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About HyperHEP B

Overview

HyperHEP B is a human hepatitis B immune globulin medicine made from donated human plasma. It is used to help prevent hepatitis B after exposure to the virus. It supplies antibodies against hepatitis B, providing short-term protection. The label recommends using it with hepatitis B vaccine for both short- and long-term protection.

What it treats

Prevention of hepatitis B after exposure to the hepatitis B virus (post-exposure prophylaxis).

Safety information

Side effects

Possible side effects include pain and tenderness at the injection site and hives. Swelling beneath the skin (angioedema) may also occur and requires urgent medical attention. Severe allergic reactions (anaphylaxis) have rarely been reported after injections of human immune globulin preparations and require immediate emergency care.

When to call your doctor

- Seek medical attention immediately for hives (raised, itchy welts). - Seek medical attention immediately for sudden swelling under the skin.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Interactions

HyperHEP B may interfere with some live virus vaccines, although it did not interfere with measles vaccination. The label recommends delaying live virus vaccines until approximately 3 months after receiving HyperHEP B. Tell your doctor about any planned vaccinations. Hepatitis B vaccine may be given at the same time as HyperHEP B at a different injection site without affecting the immune response. No interactions with other products are known.

Using HyperHEP B

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label HYPERHEP B (HEPATITIS B IMMUNE GLOBULIN (HUMAN)) INJECTION [GRIFOLS USA, LLC] (DailyMed, retrieved 19 September 2026).

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