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Evista
Raloxifene
$99.00
60mg · 3 × 28 tablets · 3 months supply
GenericGeneric medicine
$33.00 per month
How long a supply?
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Annual cost
$429a year at this pack size
Prescription required
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FDA boxed warningIncreased risk of venous thromboembolism and death from stroke
Increased risk of deep vein thrombosis and pulmonary embolism have been reported with EVISTA
. Women with active or past history of venous thromboembolism should not take EVISTA
Increased risk of death due to stroke occurred in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events. Consider risk-benefit balance in women at risk for stroke
About Evista
Overview
Evista (raloxifene hydrochloride) is a prescription medicine called a selective estrogen receptor modulator (SERM). It is used to treat and prevent osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women who have osteoporosis or are at high risk for invasive breast cancer. It acts like estrogen in bone to reduce bone breakdown and blocks estrogen activity in some other tissues. Evista is not used to treat breast cancer, prevent its recurrence or reduce the risk of noninvasive breast cancer.
What it treats
- Treatment and prevention of osteoporosis in postmenopausal women. - Reduction of invasive breast cancer risk in postmenopausal women with osteoporosis or at high risk for invasive breast cancer. Evista is not used to treat invasive breast cancer, reduce the risk of breast cancer recurrence, or reduce the risk of noninvasive breast cancer.
Safety information
Side effects
Common side effects include hot flashes, leg cramps, swelling of the hands or feet, flu-like symptoms, joint pain and sweating. Serious risks include blood clots in the deep veins, lungs or veins of the eye. Contact a doctor immediately if a blood clot is suspected. Evista also increased the risk of death due to stroke in a trial involving postmenopausal women with coronary heart disease or an increased risk of major coronary events, although the overall risk of stroke was not increased in that trial. Suspected stroke requires immediate medical attention.
FDA boxed warning
Increased risk of venous thromboembolism and death from stroke
Increased risk of deep vein thrombosis and pulmonary embolism have been reported with EVISTA
. Women with active or past history of venous thromboembolism should not take EVISTA
Increased risk of death due to stroke occurred in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events. Consider risk-benefit balance in women at risk for stroke
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
Before taking this medicine
Do not take Evista if you are pregnant or have ever had a blood clot in a vein, including deep vein thrombosis, a clot in the lungs (pulmonary embolism), or a clot in a retinal vein in the eye. Evista increases the risk of these blood clots. It should be stopped 72 hours before and during prolonged periods of immobility. Use requires caution if you have liver impairment or are at risk of stroke. In a trial involving postmenopausal women with coronary heart disease or an increased risk of major coronary events, Evista increased the risk of death due to stroke, although the overall risk of stroke was not increased. Evista should not be used to prevent cardiovascular disease. Use is not recommended before menopause or together with systemic estrogens. If previous estrogen treatment caused high triglyceride levels, blood triglycerides should be monitored. Safety and effectiveness in children have not been established.
Interactions
Tell your doctor if you take cholestyramine, warfarin, diazepam, diazoxide or lidocaine. Cholestyramine reduces raloxifene absorption and its recycling in the body, so using it with Evista is not recommended. If you take warfarin, your doctor should monitor your blood-clotting time (prothrombin time) when you start or stop Evista. Medicines that bind strongly to blood proteins, including diazepam, diazoxide and lidocaine, should be used with Evista cautiously.
Using Evista
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label EVISTA (RALOXIFENE HYDROCHLORIDE) TABLET [ELI LILLY AND COMPANY] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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