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Diovan HCT
Valsartan / Hydrochlorothiazide
$87.00
80/12.5mg · 3 × 28 tablets · 3 months supply
BrandBranded medicine· By Novartis
$29.00 per month
Strength
How long a supply?
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Annual cost
$377a year at this pack size
Prescription required
Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.
80/12.5mg
160/12.5mg
160/25mg
FDA boxed warningFetal toxicity
When pregnancy is detected, discontinue Diovan HCT as soon as possible.
Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
About Diovan HCT
Overview
Diovan HCT is a combination tablet containing valsartan and hydrochlorothiazide. It treats high blood pressure and may be used when one medicine alone is not enough or when more than one medicine is likely to be needed. Valsartan blocks a substance that narrows blood vessels, while hydrochlorothiazide helps the kidneys remove more salt and water through urine.
What it treats
- High blood pressure (hypertension), when one medicine alone is not enough or when more than one medicine is likely to be needed to reach blood pressure goals.
Safety information
Side effects
Reported side effects include inflammation of the nose and throat (nasopharyngitis), headache and dizziness. Headache and dizziness were the most common reasons people stopped treatment. Contact a doctor if you develop signs of low blood pressure or a fluid or electrolyte imbalance. Other serious concerns include kidney function problems, changes in potassium levels, new or worsening systemic lupus erythematosus, and acute angle-closure glaucoma, a serious eye condition. Kidney function and potassium levels may need monitoring in susceptible patients.
FDA boxed warning
Fetal toxicity
When pregnancy is detected, discontinue Diovan HCT as soon as possible.
Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Diovan HCT if you cannot produce urine (anuria), are allergic to any of its ingredients or to other sulfonamide-derived medicines, or have diabetes and take aliskiren. Conditions requiring caution include low blood pressure, fluid depletion, fluid or electrolyte imbalances, and systemic lupus erythematosus, which may develop or worsen. Fluid depletion should be corrected before treatment. Kidney function and potassium levels should be monitored in susceptible patients. Acute angle-closure glaucoma is also a warning associated with this medicine. Breastfeeding is not recommended during treatment.
Interactions
Lithium can build up in the blood and cause toxicity when taken with Diovan HCT. Blood lithium levels need monitoring during combined use. Potassium supplements, potassium-containing salt substitutes, potassium-sparing diuretics such as spironolactone, triamterene or amiloride, and other medicines that raise potassium, such as heparin, can increase blood potassium levels. Potassium monitoring may be needed. Other medicines that act on the renin-angiotensin system, including ACE inhibitors, other angiotensin receptor blockers and aliskiren, can increase the risk of low blood pressure, high potassium and kidney problems, including acute kidney failure. These combinations should generally be avoided. Aliskiren must not be combined with Diovan HCT in people with diabetes and should be avoided in people with reduced kidney function. NSAIDs, including COX-2 inhibitors, can reduce the blood-pressure-lowering and diuretic effects of Diovan HCT and increase the risk of kidney problems. This risk is greater in older adults, people who are dehydrated and those with impaired kidney function. Kidney function and treatment effects may need monitoring. Diabetes medicines, including insulin, may need adjustment by the prescriber. Carbamazepine may cause low blood sodium with symptoms when used with Diovan HCT. Cyclosporine may increase uric acid levels and the risk of gout-related problems. Cholestyramine and colestipol can reduce absorption of hydrochlorothiazide. Ask your doctor how to manage this interaction.
Using Diovan HCT
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label DIOVAN HCT (VALSARTAN AND HYDROCHLOROTHIAZIDE) TABLET, FILM COATED [NOVARTIS PHARMACEUTICALS CORPORATION] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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