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Dexamethasone
Dexamethazone
$51.00
0.5mg · 3 × 30 tablets · 3 months supply
GenericGeneric medicine· By Rekah
$17.00 per month
Strength
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Annual cost
$204a year at this pack size
Prescription required
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0.5mg
2mg
About Dexamethasone
Overview
Dexamethasone is a prescription synthetic steroid medicine taken as tablets. It is used for severe allergic conditions that have not responded to usual treatment, as well as certain inflammatory, autoimmune and adrenal gland disorders. It is also used for acute flare-ups of multiple sclerosis and to help manage symptoms of leukemia and lymphoma.
What it treats
- Severe allergic conditions that have not responded to conventional treatment, including asthma, allergic rhinitis, dermatitis and drug hypersensitivity reactions. - Certain severe skin diseases, including pemphigus and Stevens-Johnson syndrome. - Adrenal insufficiency, congenital adrenal hyperplasia, cancer-related high calcium levels and thyroid inflammation without pus formation. Hydrocortisone or cortisone is preferred for adrenal insufficiency. - Regional enteritis and ulcerative colitis during critical periods. - Certain blood disorders, including autoimmune hemolytic anemia, Diamond-Blackfan anemia, pure red cell aplasia and selected low-platelet disorders. - Leukemias and lymphomas, for palliative management. - Acute multiple sclerosis flare-ups and brain swelling associated with brain tumors, brain surgery or head injury. - Certain inflammatory eye conditions and temporal arteritis. - Nephrotic syndrome that is idiopathic or caused by lupus, to increase urine output or reduce protein loss in urine. - Certain lung diseases, including symptomatic sarcoidosis, berylliosis and idiopathic eosinophilic pneumonias. - Arthritis and rheumatic conditions, often as short-term additional treatment, plus dermatomyositis, polymyositis and systemic lupus erythematosus. - Certain severe forms of tuberculosis, only alongside appropriate tuberculosis treatment, and trichinosis affecting the nervous system or heart muscle.
Safety information
Side effects
Reported side effects include nausea, increased appetite, weight gain, headache, dizziness, difficulty sleeping, mood changes, acne, increased sweating and hiccups. Skin may become thin or fragile, bruise more easily or heal more slowly. The label does not state how common these effects are. Serious reported side effects that warrant contacting a doctor include severe allergic reactions, reduced resistance to infection, high blood sugar or diabetes, reduced adrenal gland function, fluid retention, low potassium and high blood pressure. Heart rhythm problems, heart failure and blood clots have also been reported. Other serious effects include stomach or intestinal ulcers, bleeding or perforation; inflammation of the pancreas; severe depression or other mental health changes; seizures; muscle weakness, osteoporosis, fractures or tendon rupture; and eye problems such as glaucoma, cataracts or blurred vision. Growth suppression has been reported in children.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take dexamethasone tablets if you have a systemic fungal infection (a fungal infection inside the body) or are allergic to dexamethasone or any other ingredient in the tablets.
Interactions
Dexamethasone can interact with other medicines and affect some test results. Discuss the following with your doctor if you use them: Warfarin: Dexamethasone may change its blood-thinning effect, often reducing it. Frequent blood-clotting tests may be needed. Diabetes medicines may also need adjustment because dexamethasone can raise blood sugar. Potassium-depleting medicines, including diuretics and amphotericin B: Combined use can cause low potassium and requires close monitoring. Low potassium can also increase the risk of an irregular heartbeat in people taking digitalis medicines. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs): Combined use increases the risk of stomach and intestinal side effects. Dexamethasone may also increase the removal of salicylates from the body. Aspirin requires particular caution in people with low levels of the clotting factor prothrombin. Medicines that may increase dexamethasone levels or effects include macrolide antibiotics such as erythromycin and clarithromycin, antifungals such as ketoconazole and itraconazole, ritonavir, cobicistat-containing products, and estrogens, including oral contraceptives. Some combinations increase the risk of corticosteroid side effects and require monitoring. Ketoconazole can also contribute to insufficient adrenal hormone production when corticosteroids are withdrawn. Medicines that may increase the breakdown or removal of dexamethasone include barbiturates, phenytoin, carbamazepine, rifampin, ephedrine and cholestyramine. Dexamethasone may lower levels of isoniazid and some medicines processed by the liver, such as indinavir and erythromycin. Phenytoin levels may rise or fall with dexamethasone, affecting seizure control. Cyclosporine: The effects of both medicines may increase, and seizures have been reported with combined use. Anticholinesterase medicines used for myasthenia gravis may cause severe weakness when combined with corticosteroids. Thalidomide requires caution because a severe skin reaction called toxic epidermal necrolysis has been reported with combined use. Aminoglutethimide may reduce corticosteroid-related suppression of adrenal function. Vaccines may produce a weaker immune response during dexamethasone treatment. Corticosteroids may also increase the multiplication of some organisms in live vaccines. Discuss vaccination timing with your doctor; the label advises delaying routine vaccines until corticosteroid treatment has ended, if possible. Dexamethasone may suppress reactions to skin tests. Indomethacin can cause false-negative results in the dexamethasone suppression test, so tell the clinician interpreting the test if you take it.
Using Dexamethasone
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label DEXAMETHASONE TABLET [REMEDYREPACK INC.] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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