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Copaxone
Glatiramer acetate
$7131.00
20mg/ml - 28 PFS · 3 × 1 package · 3 months supply
BrandBranded medicine· By Teva
$2377.00 per month
Strength
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Annual cost
$30901a year at this pack size
Prescription required
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20mg/ml - 28 PFS
40mg/mL - 12 pens
FDA boxed warningAnaphylactic reactions
ANAPHYLACTIC REACTIONS
Cases of
life-threatening and fatal anaphylaxis have been reported with COPAXONE. Anaphylaxis can occur at any time following initiation of therapy, from as early as after the first dose, up to years following initiation of therapy.
Make patients aware of the symptoms of anaphylaxis, which may overlap with those of an immediate post-injection reaction; instruct them to seek immediate medical care should these symptoms occur. Prompt identification of anaphylaxis is important to avoid a delay in treatment.
COPAXONE is contraindicated in patients with a history of hypersensitivity reactions to COPAXONE, including anaphylaxis. If an anaphylactic reaction occurs, treatment with COPAXONE must be immediately discontinued. Unless a clear alternative etiology is identified, COPAXONE must be permanently discontinued.
Life-threatening and fatal anaphylaxis, which can occur at any time following initiation of therapy (from as early as after the first dose, up to years after initiation of treatment), has been reported in patients receiving COPAXONE.
Make patients aware of the symptoms of anaphylaxis, which may overlap with those of an immediate post-injection reaction. Prompt identification of anaphylaxis is important to avoid a delay in treatment.
About Copaxone
Overview
Copaxone contains glatiramer acetate and is given as an injection under the skin. It treats relapsing forms of multiple sclerosis (MS) in adults, including clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease. How it works is not fully understood, but it is thought to modify immune processes involved in MS.
What it treats
- Clinically isolated syndrome in adults - Relapsing-remitting multiple sclerosis (MS) in adults - Active secondary progressive MS in adults
Safety information
Side effects
Common side effects include injection-site reactions. Other common effects reported in clinical studies include widening of blood vessels (which may cause flushing), rash, shortness of breath and chest pain. Serious reactions include anaphylaxis, a severe allergic reaction. Seek urgent medical help for difficulty breathing, throat tightness, hives or chest pain. A reaction can occur within seconds to minutes after an injection, with flushing, chest pain, a pounding or fast heartbeat, anxiety, shortness of breath, throat tightness or hives. Contact your doctor if you notice loss of fat beneath the skin or skin damage at an injection site, or signs or symptoms of liver problems. Liver injury and skin tissue death have been reported. Use proper injection technique and rotate injection sites as instructed. Copaxone can also alter the immune response.
FDA boxed warning
Anaphylactic reactions
ANAPHYLACTIC REACTIONS
Cases of
life-threatening and fatal anaphylaxis have been reported with COPAXONE. Anaphylaxis can occur at any time following initiation of therapy, from as early as after the first dose, up to years following initiation of therapy.
Make patients aware of the symptoms of anaphylaxis, which may overlap with those of an immediate post-injection reaction; instruct them to seek immediate medical care should these symptoms occur. Prompt identification of anaphylaxis is important to avoid a delay in treatment.
COPAXONE is contraindicated in patients with a history of hypersensitivity reactions to COPAXONE, including anaphylaxis. If an anaphylactic reaction occurs, treatment with COPAXONE must be immediately discontinued. Unless a clear alternative etiology is identified, COPAXONE must be permanently discontinued.
Life-threatening and fatal anaphylaxis, which can occur at any time following initiation of therapy (from as early as after the first dose, up to years after initiation of treatment), has been reported in patients receiving COPAXONE.
Make patients aware of the symptoms of anaphylaxis, which may overlap with those of an immediate post-injection reaction. Prompt identification of anaphylaxis is important to avoid a delay in treatment.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Copaxone if you have a known allergy to glatiramer acetate or mannitol. Allergic reactions have included anaphylaxis. Reactions can occur within seconds to minutes after injection, including flushing, chest pain, a pounding or fast heartbeat, anxiety, difficulty breathing, throat tightness or hives. These reactions generally pass on their own. Chest pain can also occur separately and is usually temporary. Copaxone may cause loss of fat under the skin or death of skin tissue at injection sites. Proper injection technique and rotating injection sites are important. It can also alter the immune response and cause liver injury. If signs or symptoms of liver problems occur, your prescriber may consider stopping treatment. If using an optional autoinjector, it must be compatible with TEVA’s Copaxone. An incompatible device may result in a missed or incomplete dose.
Interactions
Interactions between glatiramer acetate and other medicines have not been fully studied. Tell your doctor about all prescription and non-prescription medicines, vitamins, herbal products and supplements you use, especially other treatments for multiple sclerosis. No specific food interactions are known.
Using Copaxone
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use and how long it may be kept at room temperature afterwards. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label COPAXONE (GLATIRAMER ACETATE) INJECTION, SOLUTION [TEVA NEUROSCIENCE, INC.] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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