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Voranigo
Vorasidenib
$119460.00
10mg · 3 × 1 tablets · 3 months supply
BrandBranded medicine· By Servier
$39820.00 per month
Strength
How long a supply?
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Annual cost
$477840a year at this pack size
Prescription required
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10mg
40mg
About Voranigo
Overview
Voranigo is a prescription tablet containing vorasidenib. It is used after surgery, including biopsy, to treat Grade 2 astrocytoma or oligodendroglioma in adults and children aged 12 years and older whose tumour has a susceptible IDH1 or IDH2 mutation confirmed by an FDA-approved test. It works by blocking the IDH1 and IDH2 enzymes.
What it treats
- Grade 2 astrocytoma or oligodendroglioma in adults and children aged 12 years and older with a susceptible IDH1 or IDH2 mutation confirmed by an FDA-approved test, following surgery, including biopsy or partial or complete tumour removal.
Safety information
Side effects
Common side effects include tiredness, headache, COVID-19, muscle and bone pain, diarrhea, nausea and seizures. Voranigo can cause serious liver problems, including liver failure, liver tissue damage and autoimmune hepatitis. Contact your doctor about seizures or concerns about liver problems. Liver blood tests are needed every 2 weeks for the first 2 months, then monthly for the first 2 years, and as clinically needed. Severe blood test changes can include increased liver enzymes and reduced neutrophils, a type of white blood cell. Voranigo can harm an unborn baby. Use effective nonhormonal contraception and contact your doctor if you become pregnant.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
The FDA label lists no contraindications for Voranigo. However, it can cause serious liver injury, including liver failure, liver tissue damage and autoimmune hepatitis. Liver function tests are required every 2 weeks for the first 2 months, then monthly for the first 2 years, and as clinically needed. Depending on severity, the prescriber may pause, adjust or stop treatment. Voranigo can harm an unborn baby. Effective nonhormonal contraception should be used. Do not breastfeed during treatment. Voranigo may also impair fertility in males and females.
Interactions
Tell your doctor about all medicines you take. Voranigo should not be used with strong or moderate CYP1A2 inhibitors, moderate CYP1A2 inducers, or certain medicines processed by CYP3A where even a small change in their level could reduce their effectiveness. Your doctor can check whether these interactions apply to your medicines. Avoid smoking tobacco while taking Voranigo. Voranigo may reduce the effectiveness of hormonal contraception. If using them together cannot be avoided, use a nonhormonal contraceptive method.
Using Voranigo
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label VORANIGO (VORASIDENIB) TABLET, FILM COATED [SERVIER PHARMACEUTICALS LLC] (DailyMed, retrieved 19 September 2026).
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