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Valcyte-NA
Valganciclovir
$8145.00
450mg · 3 × 60 tablets · 6 months supply
BrandBranded medicine· By Roche
$1357.50 per month
How long a supply?
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Annual cost
$16290a year at this pack size
Prescription required
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FDA boxed warningHematologic toxicity, impairment of fertility, fetal toxicity, mutagenesis and carcinogenesis
CARCINOGENESIS
Hematologic Toxicity: Severe leukopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, and bone marrow failure including aplastic anemia have been reported in patients treated with valganciclovir
Impairment of Fertility: Based on animal data, and limited human data, valganciclovir may cause temporary or permanent inhibition of spermatogenesis in males and suppression of fertility in females
Fetal Toxicity: Based on animal data, valganciclovir has the potential to cause birth defects in humans
About Valcyte-NA
Overview
Valcyte-NA contains valganciclovir, an antiviral medicine active against cytomegalovirus (CMV). It is used to treat CMV retinitis, an eye infection, in adults with AIDS. It is also used to prevent CMV disease in high-risk adults receiving kidney, heart or kidney-pancreas transplants, and in high-risk children receiving kidney or heart transplants. It works by blocking an enzyme CMV needs to copy its genetic material.
What it treats
- Treatment of cytomegalovirus (CMV) retinitis in adults with AIDS. - Prevention of CMV disease in adults at high risk after a kidney, heart, or kidney-pancreas transplant. - Prevention of CMV disease in children at high risk after a kidney or heart transplant.
Safety information
Side effects
Common side effects in adults include diarrhea, fever, tiredness, nausea, vomiting, shaking, headache, trouble sleeping and urinary tract infections. Blood tests may show low levels of white blood cells, red blood cells or platelets. In children who have received a solid organ transplant, common effects include diarrhea, fever, upper respiratory tract infections, urinary tract infections, vomiting, headache and low white blood cell counts. Serious risks that warrant contacting a doctor include blood cell disorders and sudden kidney failure. Kidney failure may occur in older adults, people taking other medicines that can harm the kidneys, or people who are not adequately hydrated. Kidney function should be monitored. Other serious risks include impaired fertility, harm to an unborn baby, genetic damage and cancer. Discuss these risks with your doctor.
FDA boxed warning
Hematologic toxicity, impairment of fertility, fetal toxicity, mutagenesis and carcinogenesis
CARCINOGENESIS
Hematologic Toxicity: Severe leukopenia, neutropenia, anemia, thrombocytopenia, pancytopenia, and bone marrow failure including aplastic anemia have been reported in patients treated with valganciclovir
Impairment of Fertility: Based on animal data, and limited human data, valganciclovir may cause temporary or permanent inhibition of spermatogenesis in males and suppression of fertility in females
Fetal Toxicity: Based on animal data, valganciclovir has the potential to cause birth defects in humans
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
Before taking this medicine
Do not take valganciclovir if you have had a clinically significant allergic reaction, such as anaphylaxis, to valganciclovir, ganciclovir or any ingredient in the tablet. Acute kidney failure may occur, particularly in older adults, people taking other medicines that can harm the kidneys, or people who are not adequately hydrated. Caution and kidney function monitoring are needed. People with reduced kidney function require a dose adjustment by their prescriber. Breastfeeding is not recommended while taking valganciclovir.
Interactions
Valganciclovir is converted in the body to ganciclovir, so interactions known for ganciclovir are expected with this medicine. Discuss these medicines with your doctor: • Imipenem-cilastatin: seizures have been reported with ganciclovir. Use together is not recommended unless the potential benefits outweigh the risks. • Cyclosporine or amphotericin B: may increase the risk of kidney toxicity. Kidney function should be monitored. • Mycophenolate mofetil: may increase the risk of blood and kidney toxicity, requiring monitoring. • Medicines that suppress blood cell production or can harm the kidneys, including doxorubicin, dapsone, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/sulfamethoxazole, vinblastine, vincristine and zidovudine: combined use should be considered only when the potential benefits outweigh the risks. • Didanosine: its levels may increase, requiring close monitoring for toxicity, including inflammation of the pancreas. • Probenecid: may increase ganciclovir levels, requiring monitoring for toxicity. If you have reduced kidney function, taking valganciclovir with other medicines cleared by the kidneys may increase levels of both medicines. Close monitoring for toxicity is needed.
Using Valcyte-NA
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label VALGANCICLOVIR TABLET, FILM COATED [AMERICAN HEALTH PACKAGING] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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