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Urocit‑K
Potassium Citrate
$294.00
10 MEQ · 3 × 100 tablets · 3 months supply
BrandBranded medicine· By Mission Pharmacal
$98.00 per month
How long a supply?
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Annual cost
$1078a year at this pack size
Prescription required
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About Urocit‑K
Overview
Urocit‑K is a prescription medicine containing potassium citrate in extended-release tablets. It is used to manage renal tubular acidosis with calcium stones, calcium oxalate kidney stones associated with low citrate in the urine, and uric acid stones with or without calcium stones. It works by making urine less acidic and increasing urinary citrate, which helps reduce the crystallization of certain stone-forming salts.
What it treats
• Renal tubular acidosis (RTA) with calcium kidney stones. • Calcium oxalate kidney stones associated with low citrate levels in the urine, regardless of cause. • Uric acid kidney stones, with or without calcium stones.
Safety information
Side effects
Reported side effects include abdominal discomfort, nausea, vomiting, diarrhea or loose bowel movements. Taking Urocit-K with meals or snacks may help reduce these symptoms. The tablet’s matrix may appear intact in the stool. Urocit-K can cause dangerously high blood potassium, which may develop rapidly without symptoms and can lead to cardiac arrest or death. This risk is especially important in people whose bodies cannot remove potassium properly, including those with chronic kidney failure or heart failure. Monitoring may include blood tests and ECGs. Serious stomach or bowel injury, including bleeding, blockage or perforation, may occur. Stop taking Urocit-K immediately and seek urgent medical attention if you develop severe vomiting, abdominal pain or gastrointestinal bleeding.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Urocit-K if you have high blood potassium or a condition that increases this risk, including chronic kidney failure, uncontrolled diabetes, acute dehydration, adrenal insufficiency or extensive tissue breakdown. Strenuous exercise when you are not physically conditioned also increases this risk. Do not take it with potassium-sparing medicines such as triamterene, spironolactone or amiloride. Urocit-K must not be used if you have: • Reduced kidney function with a glomerular filtration rate below 0.7 mL/kg/min. • A condition that slows or blocks tablet passage through the digestive tract, such as delayed stomach emptying, compression of the food pipe, or narrowing or blockage of the intestine. This restriction also applies if you take anticholinergic medicines. • Peptic ulcer disease. • An active urinary tract infection. Avoid Urocit-K if you have a condition that limits potassium removal from the body, such as severe heart muscle damage or heart failure. Dangerously high potassium can develop rapidly without symptoms and may cause cardiac arrest. Periodic blood tests and ECGs are needed to monitor for this risk. Stop taking Urocit-K immediately and seek medical attention if you develop severe vomiting, abdominal pain or gastrointestinal bleeding. These symptoms require investigation for a blockage or a hole in the bowel. During pregnancy or breastfeeding, Urocit-K should be used only if clearly needed. Its effects on an unborn baby, reproductive capacity and the potassium content of breast milk are unknown. Safety and effectiveness in children have not been established.
Interactions
Urocit-K should not be taken with potassium-sparing diuretics such as triamterene, spironolactone or amiloride, because the combination can cause severely high blood potassium. Tell your doctor if you take: • ACE inhibitors, angiotensin receptor blockers (ARBs), eplerenone or aliskiren. These medicines can increase potassium levels, so close potassium monitoring is needed. • Nonsteroidal anti-inflammatory drugs (NSAIDs). These can cause potassium retention, so close potassium monitoring is needed. • Medicines that slow the movement of food through the digestive tract, such as anticholinergics. These can increase irritation of the stomach and intestines caused by potassium salts.
Using Urocit‑K
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label UROCIT-K (POTASSIUM CITRATE) TABLET, EXTENDED RELEASE [MISSION PHARMACAL COMPANY] (DailyMed, retrieved 19 September 2026).
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