Trelstar, illustration of pre-filled syringe form (not a photo of the actual pack)

Illustrative image.

Trelstar

Triptorelin Pamoate

Prescription required

$1300.00

22.5mg · 1 syringes · 6 months supply

BrandBranded medicine· By Debiopharm

$216.67 per month

How long a supply?

6 months$216.67 a month
Supplied from Israel

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Annual cost

$2600a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

About Trelstar

Overview

Trelstar is a prescription medicine containing triptorelin pamoate. It is used to treat advanced prostate cancer. It works by mimicking the activity of a hormone called gonadotropin-releasing hormone (GnRH).

What it treats

Advanced prostate cancer.

Safety information

Side effects

Common side effects include hot flushes, erectile dysfunction and shrinking of the testicles. Serious side effects that require medical attention include: - Severe allergic reactions, including anaphylactic shock and angioedema (swelling). - Temporary worsening of prostate cancer during the first few weeks of treatment, which may cause spinal cord compression or blockage of the urinary tract. - Metabolic changes, including high blood sugar, diabetes, high blood fats and non-alcoholic fatty liver disease. - Heart attack, sudden cardiac death and stroke. - Seizures, even in people without known risk factors. - Severe skin reactions. - Prolongation of the QT interval, a change in the heart’s electrical activity. Contact a doctor if you develop signs or symptoms of a serious reaction. Severe allergic reactions, symptoms of a heart attack or stroke, and seizures require urgent medical attention. Your doctor may monitor blood sugar, blood fats and cardiovascular health during treatment. Trelstar may also harm an unborn baby.

When to call your doctor

- Seek immediate help for a severe allergic reaction, including swelling of the face, lips or throat. - Seek immediate help for a seizure. - Seek immediate help for a severe skin reaction. - Seek immediate help if you have difficulty passing urine or cannot pass urine.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not use Trelstar if you have a known allergy to triptorelin, any other ingredient in the product, GnRH or other GnRH agonists. Conditions requiring caution and monitoring include: • Risk of spinal cord compression or urinary tract blockage. Testosterone may rise temporarily during the first few weeks of treatment, which can worsen prostate cancer and lead to these complications. • Metabolic problems, including high blood sugar, diabetes, high blood fats and non-alcoholic fatty liver disease. GnRH agonists may increase these risks. • Cardiovascular disease. An increased risk of heart attack, sudden cardiac death and stroke has been reported in men. • Seizures, which have occurred with or without predisposing risk factors. • Risk of a prolonged QT interval, a change in the heart’s electrical activity. The risks and benefits of treatment should be considered. Severe allergic reactions, including anaphylactic shock and angioedema, have been reported. If a reaction occurs, Trelstar must be stopped and appropriate medical care started. Treatment must be interrupted if signs of a severe skin reaction develop and permanently stopped if the reaction is confirmed. Trelstar may harm an unborn baby and may impair fertility.

Interactions

No drug interaction studies have been conducted with Trelstar. As a precaution, medicines that raise prolactin levels should not be used with Trelstar, because high prolactin levels reduce the number of GnRH receptors in the pituitary gland. Ask your doctor whether any medicines you take raise prolactin levels.

Using Trelstar

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label TRELSTAR (TRIPTORELIN PAMOATE) KIT [VERITY PHARMACEUTICALS INC.] (DailyMed, retrieved 19 September 2026).

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