Seroquel XR

Before taking this medicine

Do not take Seroquel XR if you are allergic to quetiapine or any of its ingredients. Severe allergic reactions, including anaphylaxis, have been reported. Conditions that require caution or monitoring include: • Heart or blood vessel disease, including disease affecting blood flow to the brain, because of the risk of low blood pressure. • Dementia-related psychosis in older adults, as atypical antipsychotics have been associated with an increased risk of stroke and transient ischemic attack. • Diabetes or risk factors for diabetes. Blood glucose, blood fats and weight may need monitoring. • A low white blood cell count or a history of low white blood cells or neutrophils. Frequent blood counts are needed during the first few months of treatment. • Urinary retention, an enlarged prostate or constipation, or use of other medicines with anticholinergic effects. • Pregnancy, particularly exposure during the third trimester, which may cause movement-related or withdrawal symptoms in the newborn. Blood pressure should be monitored in children and adolescents. Eye lens examinations are recommended when treatment starts and every six months during long-term treatment because lens changes have been reported. Neuroleptic malignant syndrome requires immediate discontinuation and close monitoring; tardive dyskinesia may also require treatment to be stopped by the prescriber.