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Oruvail
Ketoprofen
$245.00
200mg · 100 tablets · 3 months supply
GenericGeneric medicine
$81.67 per month
How long a supply?
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Annual cost
$980a year at this pack size
Prescription required
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FDA boxed warning
BOXED WARNING
Cardiovascular Thrombotic Events
Ketoprofen Capsules, USP is contraindicated in the setting of coronary artery bypass graft (CABG) surgery..
Gastrointestinal Risk
NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal (GI) events (see
WARNINGS ).
1 Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug.
About Oruvail
Overview
Oruvail contains ketoprofen, a non-steroidal anti-inflammatory drug (NSAID). It is used to manage the signs and symptoms of rheumatoid arthritis and osteoarthritis. It is also used to manage pain and treat primary dysmenorrhea (period pain).
What it treats
- Signs and symptoms of rheumatoid arthritis - Signs and symptoms of osteoarthritis - Pain - Primary dysmenorrhea (menstrual pain)
Safety information
Side effects
Common side effects include indigestion, nausea, stomach pain, diarrhoea, constipation, gas, vomiting, reduced appetite and mouth inflammation. Headache, dizziness, drowsiness, difficulty sleeping, nervousness, ringing in the ears, vision changes and rash may also occur. Reduced kidney function, swelling and urinary tract irritation have also been reported. Contact a doctor promptly for serious side effects, including: • Stomach or intestinal ulcers, bleeding or perforation. Report black stools, rectal bleeding or vomiting blood. • Kidney inflammation or kidney failure, including blood in the urine or swelling. • Liver problems, including hepatitis and liver failure. Yellowing of the skin or eyes needs prompt medical assessment. • Anaemia, low platelet counts or other blood disorders, which may cause unusual bleeding or bruising. • High blood pressure, a fast or pounding heartbeat, or heart failure. Seek emergency medical help for a severe allergic reaction, including swelling of the face or throat, wheezing or difficulty breathing. Blistering or peeling skin may indicate a severe skin reaction, including Stevens–Johnson syndrome or toxic epidermal necrolysis, and also needs emergency assessment. Ketoprofen can trigger severe breathing reactions in people with aspirin-sensitive asthma and must not be used by people with this sensitivity. Kidney risks are higher in older adults and people with kidney disease, heart failure or liver problems, or those taking diuretics. People with bleeding disorders or taking anticoagulants need careful monitoring.
FDA boxed warning
BOXED WARNING
Cardiovascular Thrombotic Events
Ketoprofen Capsules, USP is contraindicated in the setting of coronary artery bypass graft (CABG) surgery..
Gastrointestinal Risk
NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal (GI) events (see
WARNINGS ).
1 Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take ketoprofen if you are allergic to it, or if aspirin or another non-steroidal anti-inflammatory drug (NSAID) has caused asthma, hives or another allergic reaction. Severe, sometimes fatal allergic reactions have been reported in these patients. Ketoprofen must not be used in connection with coronary artery bypass graft (CABG) surgery. Tell your prescriber if you have asthma, kidney problems, heart failure, liver disease, a bleeding disorder, or if you take diuretics or anticoagulants. These conditions and medicines may require caution and close monitoring. Older adults are also at greater risk of kidney problems. Significant kidney impairment or chronic liver disease with low blood albumin requires close monitoring. Ketoprofen can cause kidney injury, liver problems, anemia and prolonged bleeding. Your prescriber may need blood tests if you develop signs of anemia during long-term treatment. Ketoprofen should be stopped if signs of liver disease develop. Ketoprofen does not replace corticosteroids or treat low corticosteroid levels. If you take corticosteroids, do not stop them abruptly; any changes should be managed by your prescriber. Ketoprofen can also reduce fever and inflammation, making some complications harder to detect.
Interactions
Tell your doctor if you take any of the following medicines: - Aspirin: taking it with ketoprofen is generally not recommended because side effects may increase. - Warfarin: taking these medicines together increases the risk of serious stomach or intestinal bleeding and requires close monitoring. - ACE inhibitors for blood pressure: ketoprofen may reduce their blood pressure-lowering effect. - Diuretics (“water tablets”), including furosemide and thiazides: ketoprofen may reduce their effect and increase the risk of kidney failure. Close monitoring is needed. - Lithium: ketoprofen may increase lithium levels. Careful monitoring for lithium toxicity is needed. - Methotrexate: ketoprofen may slow its removal from the body, increasing its levels and toxicity. - Probenecid: it increases ketoprofen levels, so this combination is not recommended.
Using Oruvail
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label KETOPROFEN CAPSULE [MARNEL PHARMACEUTICALS, INC.] (DailyMed, retrieved 19 September 2026).
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