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Orudis
Ketoprofen
$153.00
150mg · 9 × 10 tablets · 3 months supply
BrandBranded medicine
$51.00 per month
How long a supply?
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Annual cost
$629a year at this pack size
FDA boxed warning
BOXED WARNING
Cardiovascular Thrombotic Events
ORUDIS is contraindicated in the setting of coronary artery bypass graft (CABG) surgery..
Gastrointestinal Risk
NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal (GI) events (see
WARNINGS ).
1 Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug.
About Orudis
Overview
Orudis contains ketoprofen, a non-steroidal anti-inflammatory drug (NSAID). It is used to manage the signs and symptoms of rheumatoid arthritis and osteoarthritis. It is also used to manage pain and treat primary dysmenorrhea (menstrual pain).
What it treats
- Signs and symptoms of rheumatoid arthritis - Signs and symptoms of osteoarthritis - Pain - Primary dysmenorrhea (menstrual pain)
Safety information
Side effects
Common side effects include indigestion, nausea, stomach pain, diarrhoea, constipation, wind, vomiting and reduced appetite. Headache, dizziness, drowsiness, difficulty sleeping, nervousness, ringing in the ears, changes in vision and rash can also occur. Reduced kidney function and fluid retention have also been reported. Contact a doctor promptly for unusual bruising or bleeding, yellowing of the skin or eyes, blood in the urine, swelling, or a fast or pounding heartbeat. Serious reactions reported include kidney failure, liver damage, anaemia and other blood disorders, high blood pressure and heart failure. Seek urgent medical help for vomiting blood, black or bloody stools, severe stomach pain, difficulty breathing, swelling of the face or throat, or a blistering or peeling rash. These may indicate stomach or intestinal bleeding, ulcers or perforation, a severe allergic reaction, or a serious skin reaction such as Stevens–Johnson syndrome or toxic epidermal necrolysis.
FDA boxed warning
BOXED WARNING
Cardiovascular Thrombotic Events
ORUDIS is contraindicated in the setting of coronary artery bypass graft (CABG) surgery..
Gastrointestinal Risk
NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal (GI) events (see
WARNINGS ).
1 Throughout this package insert, the term NSAID refers to a non-aspirin non-steroidal anti-inflammatory drug.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Orudis (ketoprofen) if you are allergic to ketoprofen or have had asthma, hives or an allergic-type reaction after taking aspirin or another non-steroidal anti-inflammatory drug (NSAID). Severe, sometimes fatal allergic reactions have been reported in these patients. Orudis must not be used in connection with coronary artery bypass graft (CABG) surgery. Tell your prescriber if you have asthma, kidney problems, heart failure, liver disease, anemia or a blood-clotting disorder, or if you take diuretics or anticoagulants. Older adults also need particular caution because of the risk of kidney injury. Kidney or liver disease may require close monitoring. Orudis can affect liver function, contribute to anemia and prolong bleeding time. Orudis does not replace corticosteroids or treat low corticosteroid levels. If you take corticosteroids long term, do not stop them abruptly; any changes should be managed by your prescriber. Orudis can also reduce fever and inflammation, potentially masking signs of complications.
Interactions
Ketoprofen can interact with these medicines: • Aspirin: taking it with ketoprofen is generally not recommended because side effects may increase. • Warfarin: the combination increases the risk of serious stomach or intestinal bleeding and requires close monitoring. • ACE inhibitors for high blood pressure: ketoprofen may reduce their blood-pressure-lowering effect. • Diuretics (water tablets), including furosemide and thiazides: ketoprofen may reduce their effect on salt removal and increase the risk of kidney failure. Close monitoring of kidney function and the diuretic’s effect is needed. • Lithium: ketoprofen may raise lithium levels. Careful monitoring for signs of lithium toxicity is needed. • Methotrexate: ketoprofen may slow its removal from the body, increasing blood levels and toxicity. • Probenecid: it increases ketoprofen levels in the blood, so this combination is not recommended. Raise these medicines with your doctor if you take them or are considering starting them.
Using Orudis
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ORUDIS (KETOPROFEN) CAPSULE [ALLEGIS PHARMACEUTICALS, INC.] (DailyMed, retrieved 19 September 2026).
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