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Opdivo
Nivolumab
$970.00
40mg · 1 vial
BrandBranded medicine· By Bristol-Myers Squibb
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40mg
100mg
About Opdivo
Overview
Opdivo (nivolumab) is a prescription cancer medicine supplied in a vial for intravenous use. It is used alone or with other cancer medicines for certain types and stages of melanoma, lung cancer, kidney cancer, classical Hodgkin lymphoma, and several other cancers. Its use depends on the cancer’s features and, in some cases, previous treatment. It blocks a protein called PD-1, helping release a brake on the immune system’s response to cancer cells.
What it treats
- Melanoma that cannot be removed surgically or has spread, and after complete removal of certain stages. - Non-small cell lung cancer in selected settings before or after surgery, or when recurrent or metastatic. - Malignant pleural mesothelioma that cannot be removed surgically. - Advanced renal cell carcinoma (kidney cancer). - Classical Hodgkin lymphoma, including previously untreated Stage III or IV disease and certain relapsed or progressed cases. - Recurrent or metastatic squamous cell cancer of the head and neck after platinum-based treatment. - Urothelial cancer in selected advanced cases, or after surgery when the risk of recurrence is high. - Colorectal cancer with MSI-H or dMMR biomarkers in specified unresectable or metastatic settings. - Hepatocellular carcinoma (liver cancer) that cannot be removed surgically or has spread. - Esophageal or gastroesophageal junction cancer with residual disease after preoperative chemoradiotherapy and complete surgical removal. - Advanced, recurrent or metastatic esophageal squamous cell carcinoma in specified treatment settings. - Advanced or metastatic gastric cancer, gastroesophageal junction cancer or esophageal adenocarcinoma whose tumors express PD-L1 (≥1).
Safety information
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
The FDA label lists no contraindications for Opdivo. However, important warnings and precautions apply. Opdivo can cause immune-related reactions in any organ or tissue that may be severe or fatal. These include inflammation of the lungs, bowel, liver or kidneys, hormone gland disorders, and skin reactions. Liver enzymes, kidney function and thyroid function should be checked before and periodically during treatment. Treatment may need to be paused or permanently stopped depending on the reaction. Infusion-related reactions may require the infusion to be slowed, interrupted or permanently stopped. Serious or fatal complications can occur in people who receive an allogeneic stem cell transplant (using donor cells) before or after treatment. Opdivo can harm an unborn baby. Women who could become pregnant should use effective contraception. Do not breastfeed during treatment. For multiple myeloma, combining Opdivo with a thalidomide analogue and dexamethasone is not recommended outside controlled clinical trials.
Using Opdivo
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label OPDIVO (NIVOLUMAB) INJECTION [E.R. SQUIBB & SONS, L.L.C.] (DailyMed, retrieved 19 September 2026).
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