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Lyumjev
Insulin Lispro‑aabc
$59.00
100U/ML · 5 pen
BrandBranded medicine· By Eli lilly
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100U/ML
About Lyumjev
Overview
Lyumjev contains insulin lispro-aabc, a rapid-acting insulin analog. It is used to improve blood sugar control in adults and children with diabetes mellitus. It works by helping muscle and fat cells take up sugar from the blood and reducing the amount of sugar the liver produces.
What it treats
Diabetes mellitus in adults and children, to improve blood sugar control.
Safety information
Side effects
Reported side effects include low blood sugar, reactions at injection or infusion sites, rash, itching, allergic reactions, changes in fatty tissue under the skin (lipodystrophy), and weight gain. Low blood sugar and low potassium can be life-threatening. Severe allergic reactions, including anaphylaxis, can also occur. Seek urgent medical help for these serious reactions. Fluid retention and heart failure can occur when Lyumjev is used with medicines called thiazolidinediones (TZDs). Contact your doctor if signs or symptoms of heart failure develop. Insulin pump malfunction can cause high blood sugar and ketoacidosis, which require prompt medical attention.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Lyumjev during an episode of low blood sugar (hypoglycemia), or if you are allergic to insulin lispro-aabc or any of its ingredients. Low blood sugar can be life-threatening. More frequent blood glucose checks may be needed if you have kidney or liver problems, do not recognise the warning signs of low blood sugar, or have changes to your insulin treatment, other glucose-lowering medicines, meals or physical activity. Changes to your insulin regimen should be made under close medical supervision. Use with caution if you are at risk of low potassium, which can be life-threatening; potassium monitoring may be needed. Taking Lyumjev with thiazolidinediones (TZDs) can cause fluid retention and heart failure, so monitoring for signs of heart failure is needed. Severe allergic reactions, including life-threatening anaphylaxis, can occur. Stop using Lyumjev and seek urgent medical help if a severe allergic reaction occurs. Never share a Lyumjev pen, even if the needle is changed. Check the insulin label before each injection to avoid mix-ups. If using an insulin pump, pump malfunction can cause high blood sugar and ketoacidosis; check blood glucose and use Lyumjev by injection under the skin if the pump fails.
Interactions
Other medicines and alcohol can affect how Lyumjev controls blood sugar. More frequent blood sugar checks and prescriber-led treatment adjustments may be needed. Medicines that may increase the risk of low blood sugar include other diabetes medicines, ACE inhibitors, angiotensin II receptor blockers, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs such as octreotide, and sulfonamide antibiotics. Medicines that may reduce Lyumjev’s blood sugar-lowering effect include atypical antipsychotics such as olanzapine and clozapine, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic medicines such as albuterol, epinephrine and terbutaline, and thyroid hormones. Alcohol, beta-blockers, clonidine and lithium salts may either increase or decrease Lyumjev’s blood sugar-lowering effect. Pentamidine may cause low blood sugar, sometimes followed by high blood sugar. Beta-blockers, clonidine, guanethidine and reserpine may make the warning signs of low blood sugar less noticeable. Discuss these interactions with your doctor; more frequent blood sugar monitoring may be needed.
Using Lyumjev
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use and how long it may be kept at room temperature afterwards. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label LYUMJEV (INSULIN LISPRO-AABC) INJECTION, SOLUTION LYUMJEV KWIKPEN (INSULIN LISPRO-AABC) INJECTION, SOLUTION LYUMJEV JUNIOR KWIKPEN (INSULIN LISPRO-AABC) INJECTION, SOLUTION LYUMJEV TEMPO PEN (INSULIN LISPRO-AABC) INJECTION, SOLUTION LYUMJEV KWIKPEN (INSULIN LISPRO-AABC) INJECTION, SOLUTION [ELI LILLY AND COMPANY] (DailyMed, retrieved 19 September 2026).
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