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Lexapro

Name: Lexapro
Brand: Lundbeck
Availability: InStock

Escitalopram

Prescription required

$66.00

5mg · 3 × 28 tablets · 3 months supply

Generic

$22.00 per month

Brand or generic

Generic packs carry the same active ingredient at the same strength.

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1 month$22.00 a monthOne-off$22.00

3 months$22.00 a monthOne-off$66.00

6 months$22.00 a monthOne-off$132.00

Supplied from UK

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Annual cost

$286a year at this pack size

Prescription required

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FDA boxed warningSuicidality and antidepressant drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of escitalopram or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Escitalopram is not approved for use in pediatric patients less than 12 years of age.

Read this with the rest of the clinical information

About Lexapro

Overview

Lexapro is a prescription medicine containing escitalopram, a selective serotonin reuptake inhibitor (SSRI), supplied as tablets. It is used for initial and ongoing treatment of major depressive disorder in adults and adolescents aged 12 to 17. It is also used for the acute treatment of generalized anxiety disorder in adults. It works by slowing the reabsorption of serotonin, a process called serotonin reuptake.

What it treats

- Major depressive disorder in adults and adolescents aged 12–17, for acute and maintenance treatment. - Generalized anxiety disorder (GAD) in adults, for acute treatment.

Safety information

Side effects

Common side effects of Lexapro (escitalopram) include nausea, headache, trouble sleeping, sleepiness, tiredness, increased sweating, dry mouth, dizziness, diarrhea, constipation, indigestion and reduced appetite. Sexual side effects include reduced sex drive, delayed ejaculation, difficulty getting or keeping an erection, and difficulty reaching orgasm. Contact a doctor immediately if you develop: • New or worsening depression, suicidal thoughts or behavior, agitation, panic attacks, severe restlessness or unusual changes in mood or behavior. Antidepressants increase the risk of suicidal thoughts and behavior in children, adolescents and young adults aged 18–24. All patients need close monitoring, especially during the first few months of treatment and when the dose changes. • Possible serotonin syndrome, a potentially life-threatening reaction. Symptoms can include agitation, hallucinations, fever, heavy sweating, a fast heartbeat, muscle stiffness or twitching, poor coordination, seizures, vomiting or diarrhea. The risk is higher when escitalopram is taken with other medicines that affect serotonin. • A seizure. • Episodes of unusually elevated mood or overactivity, which may indicate mania or hypomania. • Possible low blood sodium, with symptoms such as headache, difficulty concentrating, memory problems, confusion, weakness or unsteadiness that may lead to falls. Older adults, people taking diuretics and people with low body fluid levels may be at greater risk. • A prolonged erection, which has been reported with medicines in the SSRI class. Stopping escitalopram suddenly can cause dizziness, electric-shock-like sensations, anxiety, irritability, agitation, confusion, headache, tiredness, mood changes and trouble sleeping. Serious symptoms have been reported. Do not stop treatment suddenly without speaking to your prescriber.

FDA boxed warning

Suicidality and antidepressant drugs

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Seek immediate medical attention for suicidal thoughts or behavior, worsening depression, or sudden, severe changes in mood or behavior. - Get urgent help for fever with agitation or confusion, a fast heartbeat, heavy sweating, shaking, or stiff muscles. These may be signs of serotonin syndrome. - Seek immediate medical attention for a seizure. - Contact a doctor immediately for new confusion, difficulty concentrating, weakness, or unsteadiness, especially with a headache. These may be signs of low blood sodium.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Lexapro with monoamine oxidase inhibitors (MAOIs) used to treat psychiatric disorders. Do not start Lexapro while receiving linezolid or intravenous methylene blue, which also act as MAOIs. These combinations can cause potentially life-threatening serotonin syndrome. Other medicines that affect serotonin also require caution, including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone and St. John’s Wort. Serotonin syndrome can cause agitation, hallucinations, fever, sweating, a fast heartbeat, muscle stiffness or twitching, seizures, vomiting or diarrhoea. Seek urgent medical help if these symptoms occur. Tell your prescriber if you have a history of seizures, mania or hypomania, or a personal or family history of bipolar disorder. Screening for bipolar disorder is recommended before treatment. Lexapro is not approved to treat bipolar depression. Antidepressants can increase the risk of suicidal thoughts and behaviour in children, adolescents and young adults aged 18–24. All patients need close monitoring for worsening depression, suicidal thoughts or unusual behaviour, especially during the first few months and when the dose changes. Patients and caregivers should report these changes immediately to a healthcare professional. Lexapro can cause low blood sodium. Older adults, people taking diuretics and those with reduced body fluid levels may be at greater risk. Symptoms include headache, difficulty concentrating, memory problems, confusion, weakness and unsteadiness, which may lead to falls. During pregnancy, Lexapro should be used only when the potential benefit justifies the risk to the baby. Exposure late in pregnancy may cause serious newborn complications. Some studies suggest an increased risk of persistent high blood pressure in the newborn’s lungs, while others do not. Treatment decisions should also account for the risk of depression returning if treatment is stopped. Escitalopram passes into breast milk; caution and monitoring of the breastfed infant for adverse effects are needed. Safety and effectiveness have not been established for major depressive disorder in children under 12, or for generalised anxiety disorder in anyone under 18. Children and adolescents taking Lexapro need regular monitoring of weight and growth. Do not stop Lexapro abruptly. Stopping suddenly can cause withdrawal symptoms, sometimes serious; discuss stopping treatment with your prescriber.

Interactions

Alcohol is not recommended while taking Lexapro (escitalopram). Medicines and treatments to discuss with your doctor include: - MAO inhibitors (MAOIs), other medicines that affect serotonin, and medicines that act on the brain or nervous system. - Triptans, including sumatriptan: rare cases of serotonin syndrome have been reported with SSRIs and triptans. Careful monitoring is advised, especially when starting treatment or increasing the dose. Weakness, overactive reflexes and poor coordination have also been reported with sumatriptan and SSRIs. - Aspirin, NSAID pain relievers and warfarin: taking these with escitalopram may increase bleeding risk. People taking warfarin need close monitoring when escitalopram is started or stopped. - Lithium: this may increase escitalopram’s effects on serotonin. Caution and monitoring of lithium blood levels are advised. - Carbamazepine: this may increase how quickly the body clears escitalopram. - Desipramine and other medicines broken down by the liver enzyme CYP2D6: escitalopram can increase desipramine levels; the clinical importance is uncertain. Caution is advised with this group of medicines. - Metoprolol: escitalopram can increase metoprolol blood levels, although the study found no clinically significant changes in blood pressure or heart rate. - Cimetidine and pimozide: studies with racemic citalopram, rather than escitalopram, found that cimetidine increased citalopram levels and that combining pimozide with citalopram increased a measure of the heart’s electrical recovery time. If you receive electroconvulsive therapy (ECT), discuss this with your doctor. The combined use of ECT and escitalopram has not been studied clinically.

Using Lexapro

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label LEXAPRO (ESCITALOPRAM) TABLET [DIRECT RX] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

Prescribing information (professional PDF)

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