Kovaltry, illustration of injection vial form (not a photo of the actual pack)

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Kovaltry

Antihemophilic Factor (recombinant), Full‑length

Prescription required

$508.00

500 IU · 1 vial

BrandBranded medicine· By Bayer

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About Kovaltry

Overview

Kovaltry contains full-length recombinant factor VIII, a blood-clotting protein, and is used in adults and children with hemophilia A. It is used to treat and control bleeding episodes, manage bleeding around surgery, and help reduce how often bleeding occurs. It works by temporarily replacing the missing factor VIII needed for blood to clot. Kovaltry is not indicated for treating von Willebrand disease.

What it treats

For adults and children with hemophilia A (congenital factor VIII deficiency): • Treatment and control of bleeding episodes • Management of bleeding around surgery • Routine prevention to reduce the frequency of bleeding episodes Not indicated for von Willebrand disease.

Safety information

Side effects

Commonly reported side effects include fever, headache and rash. Factor VIII inhibitors, antibodies that interfere with treatment, were also commonly reported in people who had received little or no previous treatment. Serious allergic reactions, including anaphylaxis, can occur. Stop Kovaltry and seek urgent medical help if an allergic reaction occurs. Contact your doctor if bleeding is not controlled as expected; testing for factor VIII inhibitors may be needed.

When to call your doctor

- Seek immediate medical attention if bleeding is not controlled as expected. - Stop using Kovaltry and seek immediate medical attention if you have an allergic reaction. Serious allergic reactions, including anaphylaxis, are possible.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not use Kovaltry if you have a history of allergic reactions to recombinant antihemophilic factor, any other ingredient in the product, or mouse or hamster proteins. Allergic reactions, including anaphylaxis, can occur. If symptoms develop, stop treatment and seek medical care. Antibodies that block factor VIII activity can develop. If expected factor VIII levels are not reached or bleeding is not controlled as expected, testing for these antibodies is needed.

Using Kovaltry

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label KOVALTRY (ANTIHEMOPHILIC FACTOR (RECOMBINANT)) KIT [BAYER HEALTHCARE LLC] (DailyMed, retrieved 19 September 2026).

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