Keflex, illustration of tablet form (not a photo of the actual pack)

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Keflex

Cephalexin

Prescription required

$171.00

500mg · 9 × 20 tablets · 3 months supply

GenericGeneric medicine· By Vitamed

$57.00 per month

How long a supply?

1 month$57.00 a month
3 months$57.00 a month
Supplied from Israel

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Annual cost

$703a year at this pack size

Prescription required

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About Keflex

Overview

Keflex contains cephalexin, a cephalosporin antibiotic taken by mouth. It is used to treat certain bacterial infections of the respiratory tract, middle ear, skin, bones, and urinary and genital tract, including acute prostate infections. It works against bacteria that are susceptible to cephalexin and should be used only when these bacteria are known or strongly suspected to be causing the infection.

What it treats

- Respiratory tract infections - Middle ear infections (otitis media) - Skin and skin structure infections - Bone infections - Genitourinary tract infections, including acute prostatitis For infections proven or strongly suspected to be caused by bacteria susceptible to cephalexin.

Safety information

Side effects

Diarrhea was the most frequent side effect in clinical trials. Other reported effects include nausea, vomiting, indigestion, stomach inflammation and abdominal pain. Headache, dizziness, tiredness, genital or anal itching, vaginal yeast infections, vaginal inflammation or discharge, and joint pain or inflammation have also been reported. Stop taking Keflex and seek urgent medical help if you develop an allergic reaction, such as a rash, hives or swelling. Severe allergic reactions, including anaphylaxis and serious skin reactions such as Stevens–Johnson syndrome and toxic epidermal necrolysis, have been reported. Seizures also require urgent medical attention. Contact a doctor if diarrhea develops during or after treatment. Cephalexin can cause Clostridium difficile-associated diarrhea, which may lead to life-threatening inflammation of the colon. This can occur more than two months after antibiotic treatment. Other serious effects that warrant contacting a doctor include liver inflammation or jaundice, kidney inflammation, confusion or hallucinations, and blood disorders, including anemia caused by the destruction of red blood cells and reduced white blood cell or platelet counts. Cephalexin may also slow blood clotting, particularly in people with kidney or liver problems, poor nutrition, prolonged antibiotic treatment or use of blood-thinning medicines. Prolonged use may allow other organisms to overgrow and cause a new infection.

When to call your doctor

- A rash, hives or sudden swelling. - Severe diarrhea during or after treatment, even more than two months later. - A seizure. - Yellowing of the skin or eyes. - Unusual bleeding.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Keflex (cephalexin) if you have a known allergy to cephalexin or any other cephalosporin antibiotic. Tell your prescriber about previous allergic reactions to penicillins or other medicines, as cross-allergic reactions can occur. Extra caution and monitoring may be needed if you have reduced kidney function, particularly if it is severely reduced. Kidney impairment can increase the risk of toxic effects and seizures. Older adults may need particular care because reduced kidney function is more common with age. Tell your prescriber if you have liver disease, poor nutrition or take anticoagulants (blood thinners). These factors, along with prolonged antibiotic treatment, can increase the risk of delayed blood clotting. During pregnancy, cephalexin should be used only if clearly needed, as adequate studies in pregnant women are lacking. It passes into breast milk, so caution is needed when breastfeeding. Stop taking cephalexin and seek urgent medical help if an allergic reaction or seizure occurs. Serious allergic reactions, including severe skin reactions, have been reported. Diarrhea during treatment or even more than two months afterward may indicate a serious bowel infection and needs medical assessment. Anemia developing during or after treatment also needs assessment, as cephalexin can cause red blood cells to break down. Cephalexin should be used only for a proven or strongly suspected bacterial infection. Prolonged use may allow resistant organisms to grow and cause a new infection.

Interactions

Cephalexin can increase metformin levels in the blood by slowing its removal through the kidneys. If you take metformin, your doctor should monitor you carefully and may need to adjust your metformin dose. Taking probenecid with cephalexin is not recommended because probenecid slows the removal of cephalexin through the kidneys. Tell your doctor or laboratory staff that you are taking cephalexin before a urine glucose test. It may cause a false-positive result with tests using Benedict’s or Fehling’s solution.

Using Keflex

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label KEFLEX (CEPHALEXIN) CAPSULE [DIRECT RX] (DailyMed, retrieved 19 September 2026).

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