Iwilfin, illustration of tablet form (not a photo of the actual pack)

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Iwilfin

Eflornithine

Prescription required

$16990.00

192mg · 1 tablets

BrandBranded medicine· By US WorldMeds

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About Iwilfin

Overview

Iwilfin (eflornithine) is a prescription medicine supplied as tablets. It is used to reduce the risk of high-risk neuroblastoma returning in adults and children who have had at least a partial response to prior treatment using multiple medicines and treatment methods, including anti-GD2 immunotherapy. It works by blocking an enzyme needed to make polyamines, substances involved in cell growth and division.

What it treats

High-risk neuroblastoma in adults and children: to reduce the risk of relapse after at least a partial response to prior treatment using multiple medicines and treatment approaches, including anti-GD2 immunotherapy.

Safety information

Side effects

Common side effects of Iwilfin include hearing loss, middle ear infection, fever, pneumonia and diarrhea. Serious risks include reduced blood cell counts, liver damage and hearing loss. Contact your doctor if you develop hearing loss or any new or worsening side effects. Severe laboratory abnormalities can include raised liver enzymes, reduced neutrophils (a type of white blood cell) and reduced hemoglobin. Blood counts, liver function and hearing must be monitored before and during treatment. Iwilfin can harm an unborn baby. Use effective contraception if you could become pregnant, and contact your doctor if you become pregnant during treatment.

When to call your doctor

- Hearing loss. - Fever. - Diarrhea.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

The label lists no contraindications for Iwilfin. Iwilfin requires caution because it can reduce blood cell counts, cause liver damage and cause hearing loss. Blood counts, liver function and hearing should be checked before and during treatment. Depending on severity, the prescriber may pause treatment, reduce the dose or stop treatment permanently. Iwilfin can harm an unborn baby. Females who can become pregnant should use effective contraception. Do not breastfeed during treatment. Severe kidney impairment (eGFR below 30 mL/min) requires a dose reduction determined by the prescriber.

Using Iwilfin

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label IWILFIN (EFLORNITHINE HYDROCHLORIDE) TABLET [USWM, LLC] (DailyMed, retrieved 19 September 2026).

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