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Foscavir
Foscarnet Sodium
$277.00
24mg/ml · 1 vial
BrandBranded medicine· By Fresenius Kabi
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FDA boxed warning
WARNING
RENAL IMPAIRMENT IS THE MAJOR TOXICITY OF FOSCAVIR. FREQUENT MONITORING OF SERUM CREATININE, WITH DOSE ADJUSTMENT FOR CHANGES IN RENAL FUNCTION, AND ADEQUATE HYDRATION WITH ADMINISTRATION OF FOSCAVIR IS IMPERATIVE. (See ADMINISTRATION section; Hydration. )
SEIZURES, RELATED TO ALTERATIONS IN PLASMA MINERALS AND ELECTROLYTES, HAVE BEEN ASSOCIATED WITH FOSCAVIR TREATMENT. THEREFORE, PATIENTS MUST BE CAREFULLY MONITORED FOR SUCH CHANGES AND THEIR POTENTIAL SEQUELAE. MINERAL AND ELECTROLYTE SUPPLEMENTATION MAY BE REQUIRED.
FOSCAVIR IS INDICATED FOR USE ONLY IN IMMUNOCOMPROMISED PATIENTS WITH CMV RETINITIS AND MUCOCUTANEOUS ACYCLOVIR-RESISTANT HSV INFECTIONS. (See INDICATIONS section).
About Foscavir
Overview
Foscavir contains foscarnet sodium, an antiviral medicine. It comes in a vial as a sterile, preservative-free solution for administration into a vein only. It works by blocking a viral enzyme needed to copy viral DNA.
Safety information
Side effects
Frequently reported side effects in clinical trials included fever, nausea, anemia (low red blood cell count), diarrhea, vomiting and headache. These events were reported regardless of whether Foscavir caused them. Serious side effects that warrant contacting a doctor include impaired kidney function, changes in blood mineral levels, seizures, and bone marrow suppression (reduced blood cell production). Kidney impairment is Foscavir’s major toxicity. Blood mineral changes include low calcium, magnesium or potassium, and low or high phosphate. Seek urgent medical help if a seizure occurs. Kidney impairment, electrolyte changes and seizures may have contributed to deaths in clinical trials.
FDA boxed warning
WARNING
RENAL IMPAIRMENT IS THE MAJOR TOXICITY OF FOSCAVIR. FREQUENT MONITORING OF SERUM CREATININE, WITH DOSE ADJUSTMENT FOR CHANGES IN RENAL FUNCTION, AND ADEQUATE HYDRATION WITH ADMINISTRATION OF FOSCAVIR IS IMPERATIVE. (See ADMINISTRATION section; Hydration. )
SEIZURES, RELATED TO ALTERATIONS IN PLASMA MINERALS AND ELECTROLYTES, HAVE BEEN ASSOCIATED WITH FOSCAVIR TREATMENT. THEREFORE, PATIENTS MUST BE CAREFULLY MONITORED FOR SUCH CHANGES AND THEIR POTENTIAL SEQUELAE. MINERAL AND ELECTROLYTE SUPPLEMENTATION MAY BE REQUIRED.
FOSCAVIR IS INDICATED FOR USE ONLY IN IMMUNOCOMPROMISED PATIENTS WITH CMV RETINITIS AND MUCOCUTANEOUS ACYCLOVIR-RESISTANT HSV INFECTIONS. (See INDICATIONS section).
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Foscavir must not be used in people with a clinically significant allergy to foscarnet sodium.
Interactions
Foscavir can interact with medicines that affect kidney function, blood calcium levels or heart rhythm. Tell your doctor if you take: • Medicines that can harm the kidneys, including aminoglycoside antibiotics, amphotericin B, cyclosporine, acyclovir, methotrexate, tacrolimus or intravenous pentamidine. These combinations should be avoided unless the potential benefits outweigh the risks. • Intravenous pentamidine or other medicines that affect blood calcium. Foscavir can lower blood calcium, and extreme caution is needed with these combinations. Kidney problems and symptomatic low calcium, including a fatal case of severe low calcium, have been reported with intravenous pentamidine. • Diuretics (“water tablets”). Loop diuretics may slow the removal of Foscavir from the body and increase the risk of toxicity. The label recommends thiazide diuretics over loop diuretics when a diuretic is needed. • Ritonavir, with or without saquinavir. Kidney problems have been reported during combined use with Foscavir. • Medicines that prolong the QT interval, a change in the heart’s electrical activity that can lead to a dangerous abnormal rhythm. These combinations should be avoided. Examples include quinidine, procainamide, dofetilide, amiodarone, sotalol, phenothiazines, tricyclic antidepressants, and certain macrolide and fluoroquinolone antibiotics.
Using Foscavir
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label FOSCAVIR (FOSCARNET SODIUM) INJECTION, SOLUTION [CLINIGEN LIMITED] (DailyMed, retrieved 19 September 2026).
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