Floxin, illustration of tablet form (not a photo of the actual pack)

Illustrative image.

Floxin

Ofloxacin

Prescription required

$153.00

200mg · 9 × 20 tablets · 3 months supply

Generic· By Dexxon

$51.00 per month

Brand or generic

Generic packs carry the same active ingredient at the same strength.

How long a supply?

1 month$51.00 a month
3 months$51.00 a month
Supplied from Israel

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Annual cost

$629a year at this pack size

Prescription required

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200mg

FDA boxed warning

WARNING

SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS

Read this with the rest of the clinical information

About Floxin

Overview

Floxin contains ofloxacin, a prescription fluoroquinolone antibiotic taken as tablets. It treats certain bacterial infections in adults, including pneumonia and infections of the skin, urinary tract, reproductive tract and prostate. For bacterial flare-ups of chronic bronchitis and uncomplicated bladder infections, it is reserved for people with no alternative treatment options because of the risk of serious adverse reactions. It works against bacteria that are susceptible to ofloxacin.

What it treats

Ofloxacin tablets are used in adults to treat the following infections caused by susceptible bacteria. Infections are mild to moderate unless noted otherwise: - Acute bacterial flare-ups of chronic bronchitis, only when no alternative treatment options are available. - Community-acquired pneumonia. - Uncomplicated skin and skin structure infections. - Acute, uncomplicated gonorrhea affecting the urethra or cervix. - Chlamydial infections of the urethra or cervix, including mixed infections with gonorrhea. - Acute pelvic inflammatory disease, including severe infection. Additional treatment is needed if anaerobic bacteria are suspected. - Uncomplicated bladder infections (cystitis), only when no alternative treatment options are available. - Complicated urinary tract infections. - Prostatitis caused by Escherichia coli. The restrictions for bronchitis flare-ups and uncomplicated cystitis reflect the risk of serious adverse reactions with fluoroquinolones, including ofloxacin.

Safety information

Side effects

Commonly reported side effects of ofloxacin include nausea, trouble sleeping, headache, dizziness, diarrhea, vomiting, rash, itching and changes in taste. Vaginal inflammation and itching around the external genital area have also been reported. Serious reactions reported with ofloxacin or other quinolone medicines include tendon inflammation or rupture; nerve damage that may be irreversible; seizures; confusion, hallucinations or other severe mental changes; suicidal thoughts or acts; and worsening of myasthenia gravis. Contact a doctor promptly if any of these occur. Seek immediate medical help for a severe allergic reaction, swelling, difficulty breathing, a severe blistering or peeling skin reaction, or suicidal thoughts. Other serious reported effects include dangerous heart rhythm disturbances, fainting, liver damage or failure, kidney failure, blood disorders and gastrointestinal bleeding. Severe inflammation of the colon can develop during or after treatment. Contact a doctor promptly for severe diarrhea, jaundice, unusual bleeding or bruising, palpitations or fainting. High or low blood sugar has been reported, particularly in people with diabetes taking insulin or oral blood-sugar-lowering medicines. Blood tests may also show changes in blood cell counts, liver enzymes or kidney function. Not all events reported in trials or after marketing were proven to be caused by ofloxacin.

FDA boxed warning

WARNING

SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS

A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.

When to call your doctor

- Tendon pain or swelling, a suspected torn tendon, or new or worsening muscle weakness. - New numbness, tingling, or burning sensations, which may signal nerve damage. - Seizures, hallucinations, severe confusion, or thoughts of suicide. - Trouble breathing, swelling of the face or throat, or a blistering or peeling rash. - Yellowing of the skin or eyes, which may signal liver problems. Seek medical attention immediately if any of these occur.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Floxin (ofloxacin) if you have previously had an allergic reaction to ofloxacin or any other quinolone antibiotic.

Interactions

Antacids containing calcium, magnesium or aluminum, sucralfate, iron supplements, multivitamins containing zinc, and certain didanosine products can reduce ofloxacin absorption. These products should not be taken within two hours before or after ofloxacin. Check with your doctor or pharmacist if you use them. Other medicines to discuss with your doctor include: • Nonsteroidal anti-inflammatory drugs (NSAIDs): taking these with ofloxacin may increase the risk of nervous system stimulation and seizures. • Theophylline: ofloxacin may increase theophylline levels and the risk of side effects, including seizures. Your doctor should monitor theophylline levels closely. Side effects can occur even without an increase in blood levels. • Warfarin and related blood thinners: some quinolone antibiotics can increase their blood-thinning effects. Blood-clotting tests should be monitored closely when they are taken together. • Diabetes medicines, including insulin and glyburide (glibenclamide): high or low blood sugar has been reported when these are taken with quinolone antibiotics. Careful blood sugar monitoring is recommended. • Cimetidine, cyclosporine and probenecid: interactions have been reported with some other quinolone antibiotics, but their potential interactions with ofloxacin have not been studied. Interactions between ofloxacin and caffeine have not been detected.

Using Floxin

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label OFLOXACIN TABLET, FILM COATED [MODAVAR PHARMACEUTICALS LLC] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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