Erleada, illustration of tablet form (not a photo of the actual pack)

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Erleada

Apalutamide

Prescription required

$3146.00

60mg · 120 tablets · 4 months supply

BrandBranded medicine· By Janssen Cilag

$786.50 per month

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Annual cost

$9438a year at this pack size

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60mg

About Erleada

Overview

Erleada contains apalutamide, an androgen receptor inhibitor. It is used to treat prostate cancer that has spread and still responds to treatment that lowers testosterone, or prostate cancer that has not spread but is resistant to such treatment. It works by blocking androgen receptors, interfering with signals from these hormones within prostate cancer cells.

What it treats

- Metastatic castration-sensitive prostate cancer (mCSPC). - Non-metastatic castration-resistant prostate cancer (nmCRPC).

Safety information

Side effects

Common side effects of Erleada include tiredness, joint pain, rash, decreased appetite, falls, weight loss, high blood pressure, hot flushes, diarrhoea and bone fractures. Contact a doctor promptly about serious side effects, including problems with blood flow to the brain or heart, fractures, falls, seizures, severe skin reactions and lung inflammation (interstitial lung disease or pneumonitis). Falls occur more often in older people. Severe skin reactions include Stevens–Johnson syndrome, toxic epidermal necrolysis and DRESS, a reaction that can affect the skin and other organs. Treatment must be permanently stopped if a seizure occurs. Suspected severe skin reactions or lung inflammation require treatment to be interrupted while they are assessed. Confirmed severe skin reactions, severe lung inflammation, or lung inflammation with no other identified cause require permanent discontinuation.

When to call your doctor

- Seek medical attention immediately if you have a seizure. - Get immediate medical help for a severe rash or skin reaction. - Seek prompt medical attention after a fall or if you think you have broken a bone.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Interactions

Apalutamide may reduce the activity of certain medicines processed by CYP3A4, CYP2C19, CYP2C9 or UGT, or transported by P-gp, BCRP or OATP1B1. Ask your doctor to review your other medicines for these interactions, as they may become less effective.

Using Erleada

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label ERLEADA (APALUTAMIDE) TABLET, FILM COATED [JANSSEN PRODUCTS, LP] (DailyMed, retrieved 19 September 2026).

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