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Durezol
Difluprednate
$78.00
0.05% · 1 - 5ml bottle
BrandBranded medicine· By Alcon
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About Durezol
Overview
Durezol is a prescription corticosteroid eye emulsion containing difluprednate 0.05%. It is used to treat inflammation and pain associated with eye surgery, and endogenous anterior uveitis, a type of inflammation inside the front of the eye. It works by suppressing the inflammatory response, although its exact action in the eye is not fully understood.
What it treats
- Inflammation and pain associated with eye surgery. - Endogenous anterior uveitis (inflammation in the front of the eye arising from within the eye).
Safety information
Side effects
Common side effects reported after eye surgery include eye pain, redness, swelling of the cornea or the membrane covering the white of the eye, sensitivity to light, eyelid inflammation, inflammation inside the front of the eye, and clouding of the capsule behind the lens. In people treated for endogenous anterior uveitis, common side effects include blurred vision, eye irritation or pain, headache, increased pressure inside the eye, redness, and inflammation of the cornea, iris or other structures inside the eye. Contact your doctor about serious side effects, including increased eye pressure, glaucoma with optic nerve damage or vision loss, cataracts, delayed healing after cataract surgery, and breakdown or perforation of the cornea or the white outer wall of the eye in people with thinning of these tissues. Durezol can also mask or worsen bacterial eye infections, prolong or worsen viral eye infections, including herpes simplex, and increase the risk of fungal infections with long-term use. If signs and symptoms do not improve after two days, contact your doctor for reassessment. Eye pressure should be monitored if Durezol is used for 10 days or longer.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Durezol if you have most active viral infections of the cornea or conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia or varicella. It must also not be used with mycobacterial eye infections or fungal infections of eye structures. Great caution is needed if you have a history of herpes simplex. Corticosteroids used in the eye may prolong or worsen viral eye infections. They may also mask or worsen bacterial infections and increase the risk of secondary infections. Long-term use may allow fungal infections of the cornea to develop. A persistent corneal ulcer needs assessment for possible fungal infection. Prolonged use may raise eye pressure and cause glaucoma, optic nerve damage or vision problems. Eye pressure should be monitored if Durezol is used for 10 days or longer. Corticosteroids may also cause cataracts. Use after cataract surgery may delay healing and increase the risk of bleb formation. If the cornea or sclera is thinned by disease, corticosteroid use may cause a hole or tear in these tissues. If signs and symptoms do not improve after 2 days, you should be reassessed.
Using Durezol
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C away from direct light. Once opened, follow the in-use period printed on the pack and do not let the dropper touch the eye or any surface. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label DUREZOL (DIFLUPREDNATE) EMULSION [SANDOZ INC] (DailyMed, retrieved 19 September 2026).
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