Denavir, illustration of cream tube form (not a photo of the actual pack)

Illustrative image.

Denavir

Ofatumumab, Penciclovir

$30.00

1% · 1 tube

BrandBranded medicine· By Novartis

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About Denavir

Overview

Denavir is a topical antiviral cream containing penciclovir. It is used to treat recurrent cold sores in adults and children aged 12 years and older. It works by blocking an enzyme the herpes simplex virus needs to copy its DNA, limiting the virus’s ability to multiply.

What it treats

Recurrent cold sores (herpes labialis) in adults and children aged 12 years and older.

Safety information

Side effects

Local skin reactions were reported in 3% of people treated with Denavir, compared with 4% of those treated with placebo.

Before taking this medicine

Do not use Denavir if you have a known allergy to the product or any of its ingredients. It is only for topical use on cold sores on the lips and face.

Interactions

No drug interaction studies have been performed with Denavir. Because very little is absorbed into the bloodstream, interactions with medicines acting elsewhere in the body are unlikely.

Using Denavir

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C with the cap closed, away from direct light and heat. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label DENAVIR (PENCICLOVIR) CREAM [MYLAN PHARMACEUTICALS INC.] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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