Apidra

Before taking this medicine

Do not use Apidra during an episode of low blood sugar (hypoglycemia), or if you are allergic to insulin glulisine or any of its other ingredients. Apidra can cause life-threatening low blood sugar. More frequent blood sugar checks may be needed if you have kidney or liver impairment, do not notice the warning signs of low blood sugar, or have changes in your insulin treatment, other blood-sugar-lowering medicines, meals or physical activity. Changes to your insulin regimen should be made under close medical supervision. Check the insulin label before every injection to avoid mix-ups. Low blood potassium can also be life-threatening; people at risk may need potassium monitoring. Severe allergic reactions, including anaphylaxis, can occur and require stopping Apidra and urgent treatment. Taking Apidra with thiazolidinediones (TZDs) can cause fluid retention and heart failure. Your clinician should monitor for signs of heart failure and may need to adjust or stop the TZD. If you use an insulin pump, pump malfunction can cause high blood sugar and ketoacidosis. If this happens, monitor your blood sugar and give Apidra by injection under the skin.