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Abilify
Aripiprazole
$393.00
5mg · 3 × 28 tablets · 3 months supply
Generic· By UniPharm
$131.00 per month
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Generic packs carry the same active ingredient at the same strength.
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$1703a year at this pack size
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FDA boxed warningIncreased mortality in elderly patients with dementia-related psychosis and suicidal thoughts and behaviors with antidepressant drugs
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. ABILIFY is not approved for the treatment of patients with dementia-related psychosis.
Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24 years; there was a reduction in risk with antidepressant use in patients aged 65 years and older.
In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber.
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants. Monitor for worsening and emergence of suicidal thoughts and behaviors.
About Abilify
Overview
Abilify tablets contain aripiprazole, an atypical antipsychotic medicine. They are used to treat schizophrenia, acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autistic disorder, and Tourette’s disorder. They are also used as an add-on treatment for major depressive disorder. Exactly how aripiprazole works is unclear, but its effects may involve partly activating some dopamine and serotonin receptors while blocking others.
What it treats
Abilify tablets are used to treat: - Schizophrenia - Acute manic and mixed episodes associated with bipolar I disorder - Major depressive disorder, as an add-on treatment - Irritability associated with autistic disorder - Tourette’s disorder
Safety information
Side effects
Common side effects vary by age and the condition being treated. They include restlessness or an inability to sit still (akathisia), sleepiness, tiredness, difficulty sleeping, tremor, other movement problems, nausea, vomiting, constipation, dizziness, blurred vision, headache, increased saliva or drooling, and changes in appetite. Fever and nose or throat inflammation were also commonly reported in some children and adolescents. Serious side effects include neuroleptic malignant syndrome, tardive dyskinesia (involuntary movements), seizures, low white blood cell counts, difficulty swallowing, problems regulating body temperature, and a drop in blood pressure when standing. Sleepiness and impaired thinking or movement can affect the ability to operate machinery and increase the risk of falls. Contact a doctor promptly if these problems occur or are suspected. Seek immediate medical help for seizures, signs of stroke, or suicidal thoughts or behaviour. Other important risks include high blood sugar or diabetes, changes in blood fat levels, and weight gain. Blood sugar and weight monitoring may be needed. Tell a doctor promptly about new or uncontrollable gambling or other compulsive behaviours. The label warns of an increased risk of death and stroke in elderly patients with dementia-related psychosis, and suicidal thoughts and behaviours in children, adolescents and young adults. People at high risk of suicide require close supervision.
FDA boxed warning
Increased mortality in elderly patients with dementia-related psychosis and suicidal thoughts and behaviors with antidepressant drugs
Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. ABILIFY is not approved for the treatment of patients with dementia-related psychosis.
Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24 years; there was a reduction in risk with antidepressant use in patients aged 65 years and older.
In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber.
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants. Monitor for worsening and emergence of suicidal thoughts and behaviors.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Abilify if you have previously had an allergic reaction to aripiprazole. Reactions can include itching, hives or anaphylaxis, a severe allergic reaction. Conditions that require caution include: • Dementia-related psychosis in older adults, because of an increased risk of stroke or transient ischaemic attack (TIA), including fatal events. • Diabetes or risk factors for diabetes. Blood glucose should be monitored regularly. Weight gain and changes in blood fats can also occur, and weight should be monitored. • Heart or blood vessel disease, dehydration or a risk of fainting. Abilify can cause a fall in blood pressure when standing; heart rate and blood pressure may need monitoring. • A history of significantly low white blood cell counts or low counts caused by medicines. Frequent blood counts are needed during the first few months of treatment. • A history of seizures or conditions that increase seizure risk. • A high risk of suicide, which requires close supervision. Other important risks include neuroleptic malignant syndrome, which requires immediate discontinuation and close monitoring, and tardive dyskinesia, which causes involuntary movements and may require stopping treatment. New or worsening gambling urges or other compulsive behaviours may also require a treatment change. These decisions should be made by the prescriber. Use caution when operating machinery because Abilify may affect thinking and movement. Exposure during the third trimester of pregnancy may cause movement-related or withdrawal symptoms in newborns. During breastfeeding, the infant should be monitored for dehydration and inadequate weight gain.
Interactions
Tell your doctor about all medicines you take, particularly strong CYP2D6 or CYP3A4 inhibitors and strong CYP3A4 inducers. These interactions may require your prescriber to adjust your Abilify dose. Also tell your doctor if you are known to be a CYP2D6 poor metabolizer, as this affects dose adjustment, including when taking a strong CYP3A4 inhibitor.
Using Abilify
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ABILIFY (ARIPIPRAZOLE) TABLET [OTSUKA AMERICA PHARMACEUTICAL, INC.] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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