Salagen, illustration of oral solution or syrup form (not a photo of the actual pack)

Illustrative image.

Salagen

Pilocarpine

Prescription required

$669.00

5mg · 3 × 100 tablets · 3 months supply

Brand· By MGI

$223.00 per month

Brand or generic

Generic packs carry the same active ingredient at the same strength.

Strength

How long a supply?

1 month$223.00 a month
3 months$223.00 a month
6 months$185.83 a month
Supplied from Israel

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Annual cost

$2453a year at this pack size

Prescription required

Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

5mg

1%

2%

About Salagen

Overview

Salagen tablets contain pilocarpine hydrochloride, a medicine used to treat dry mouth. They treat dry mouth caused by reduced salivary gland function after radiotherapy for head and neck cancer, or associated with Sjögren’s syndrome. Pilocarpine works by activating certain receptors in the body called cholinergic receptors.

What it treats

- Dry mouth caused by reduced salivary gland function following radiotherapy for head and neck cancer. - Dry mouth in people with Sjögren’s syndrome.

Safety information

Side effects

Common side effects of Salagen tablets include sweating, more frequent urination, flushing, chills, nausea, runny nose and diarrhea. Headache, indigestion, dizziness, weakness, increased saliva, abdominal pain and vomiting were also reported. Sweating was the most common reason for stopping treatment in studies involving people with Sjögren’s syndrome. Older patients in these studies reported urinary frequency, diarrhea and dizziness more often than younger patients. Contact a doctor promptly if you experience chest pain, a fast, slow or irregular heartbeat, fainting, difficulty breathing, an allergic reaction or facial swelling. Rare serious events reported during treatment included heart attack, bleeding in the brain, liver inflammation, inflammation of the pancreas and severe skin reactions involving peeling or blisters. For these rare reports, it is not known whether pilocarpine caused the event.

When to call your doctor

- Chest pain. - Difficulty breathing. - Fainting, or a fast, slow or irregular heartbeat. - Eye pain or changes in vision. - Black, tar-like stools.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Salagen if you have uncontrolled asthma, a known allergy to pilocarpine, or a condition in which narrowing of the pupil should be avoided, such as acute iritis (inflammation of the iris) or narrow-angle (angle-closure) glaucoma.

Interactions

Tell your doctor if you take beta-blockers, as using them with pilocarpine may affect the electrical signals that control your heartbeat. Other medicines with similar effects to pilocarpine (parasympathomimetics) may increase its effects when taken together. Pilocarpine may reduce the effects of anticholinergic medicines, such as atropine and inhaled ipratropium, potentially interfering with their intended benefits. No formal drug interaction studies have been performed.

Using Salagen

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C, upright and tightly closed, away from direct light. Check the label for how long it may be used after opening. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label SALAGEN (PILOCARPINE HYDROCHLORIDE) TABLET, FILM COATED [ADVANZ PHARMA (US) CORP.] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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