Plenvu, illustration of sachet or powder form (not a photo of the actual pack)

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Plenvu

Sodium Ascorbate;Potassium Chloride

Prescription required

$46.00

112G/44 4G/55.65G · 3 sachets

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Upload your prescription after ordering, or send it to our pharmacy team. We dispense only against a valid prescription.

About Plenvu

Overview

Plenvu is an osmotic laxative supplied as powder in sachets to be mixed with water for drinking. It is used to cleanse the colon before a colonoscopy in adults. It works by keeping more water in the colon, causing loose stools that help clear the bowel.

What it treats

Cleansing the colon before a colonoscopy in adults.

Safety information

Side effects

Common side effects include nausea, vomiting, dehydration, and abdominal pain or discomfort. Serious risks include major changes in body fluid and salt levels, abnormal heart rhythms, seizures, ulcers in the lining of the colon, and inflammation caused by reduced blood flow to the colon (ischemic colitis). Aspiration, liquid entering the airways, is also a risk. Contact a doctor if you experience or suspect a serious side effect. Allergic reactions, including anaphylaxis, can occur. Seek immediate medical care if symptoms of an allergic reaction develop.

When to call your doctor

- Seek immediate medical attention if you have a seizure. - Seek immediate medical attention if you notice an irregular heartbeat. - Seek immediate medical attention if you develop an allergic reaction.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not take Plenvu if you have a blockage in the stomach or bowel, a hole in the bowel wall (perforation), stomach contents that are not emptying properly (gastric retention), a bowel that is not moving normally (ileus), toxic megacolon, or an allergy to any ingredient. Suspected blockage or perforation must be ruled out before use. Tell your prescriber if you have kidney problems, a history of seizures or an increased seizure risk, a risk of abnormal heart rhythms, known or suspected inflammatory bowel disease, difficulty swallowing or a risk of breathing liquid into your lungs, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or phenylketonuria. Plenvu contains phenylalanine. Plenvu can cause fluid and electrolyte imbalances. Adequate hydration is important. Your prescriber should review your other medicines, particularly those that affect kidney function or increase seizure risk, and may consider blood tests or heart monitoring. People at risk of breathing liquid into their lungs should be observed during use. Seek immediate medical care if symptoms of an allergic reaction occur, as serious reactions, including anaphylaxis, are possible.

Interactions

Ask your doctor whether any medicines you take could increase the risks associated with changes in body fluids and electrolyte levels during Plenvu use.

Using Plenvu

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C in a dry place, in the original sachet until you use it, away from direct light and moisture. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label PLENVU (POLYETHYLENE GLYCOL 3350, SODIUM SULFATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE, ASCORBIC ACID, SODIUM ASCORBATE) KIT [SALIX PHARMACEUTICALS, INC] (DailyMed, retrieved 19 September 2026).

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