Klisyri, illustration of ointment form (not a photo of the actual pack)

Illustrative image.

Klisyri

Tirbanibulin

Prescription required

$188.00

1% · 5 units

BrandBranded medicine

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About Klisyri

Overview

Klisyri is a topical ointment containing tirbanibulin. It is used to treat actinic keratosis on the face or scalp. Tirbanibulin blocks microtubules, but exactly how Klisyri works to treat actinic keratosis is unknown.

What it treats

Actinic keratosis on the face or scalp.

Safety information

Side effects

Common side effects of Klisyri include skin reactions, itching and pain where it is applied. Severe skin reactions can occur in the treated area, including blisters, pus-filled bumps, open sores or ulcers. Contact a doctor if these occur. Do not use Klisyri until the skin has healed from any previous medicine or surgical treatment. Klisyri may irritate the eyes if it gets into them. Avoid getting it in or around the eyes. If accidental eye exposure occurs, rinse the eyes with water and seek medical care.

When to call your doctor

- If Klisyri gets into your eyes, rinse them with water and seek medical care. - Seek medical attention for severe skin reactions in the treated area, such as blistering, pus-filled bumps or open sores.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

The label lists no contraindications for Klisyri. Avoid use until the skin has healed from any previous drug or surgical treatment. Local skin reactions can occur in the treated area and may be severe, including blisters, pus-filled bumps, open sores or ulcers. Avoid getting Klisyri in the eyes or on the skin around them, as eye exposure may cause irritation. If accidental eye exposure occurs, flush the eyes with water and seek medical care.

Using Klisyri

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C with the cap closed, away from direct light and heat. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label KLISYRI (TIRBANIBULIN) OINTMENT [ALMIRALL, LLC] (DailyMed, retrieved 19 September 2026).

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