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Kineret
Anakinra
$1400.00
100mg · 4 × 7 pre-filled syringe · 1 month supply
BrandBranded medicine· By MegaPharm
$1400.00 per month
How long a supply?
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Ships cold, in insulated packing
This medicine ships in insulated packing with coolant and carries its own shipping charge, shown at checkout.
Annual cost
$18200a year at this pack size
Prescription required
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About Kineret
Overview
Kineret (anakinra) is a medicine given by injection under the skin using a pre-filled syringe. It is used to reduce signs and symptoms and slow structural damage in adults with moderately to severely active rheumatoid arthritis after one or more disease-modifying antirheumatic drugs (DMARDs) have failed. It also treats neonatal-onset multisystem inflammatory disease (NOMID), a cryopyrin-associated periodic syndrome, and deficiency of interleukin-1 receptor antagonist (DIRA). It works by blocking the activity of interleukin-1, a protein involved in inflammation.
What it treats
- Moderately to severely active rheumatoid arthritis in adults aged 18 or older after one or more disease-modifying antirheumatic drugs (DMARDs) have failed, to reduce signs and symptoms and slow structural damage. - Neonatal-onset multisystem inflammatory disease (NOMID), a cryopyrin-associated periodic syndrome (CAPS). - Deficiency of interleukin-1 receptor antagonist (DIRA).
Safety information
Side effects
Common side effects vary by the condition being treated: • In rheumatoid arthritis: injection-site reactions, worsening arthritis, upper respiratory tract infections, headache, nausea, diarrhea, sinus infections, joint pain, flu-like symptoms and abdominal pain. • In NOMID, during the first six months: injection-site reactions, headache, vomiting, joint pain, fever and inflammation of the nose and throat. • In DIRA: upper respiratory tract infections, rash, fever, flu-like illness and inflammation of the stomach and intestines. Serious infections can occur. Contact your doctor promptly if you develop an infection. Kineret should be discontinued if a serious infection develops in someone with rheumatoid arthritis. For people with NOMID or DIRA, the doctor must weigh the risk of a disease flare from stopping against the risk of continuing treatment. Serious allergic reactions, including anaphylaxis and angioedema (swelling), and serious skin reactions, including DRESS, can occur. These require stopping Kineret and urgent medical attention. People with DIRA may have a higher risk of allergic reactions, particularly during the first several weeks of treatment. Amyloid deposits can develop at injection sites; rotating sites helps reduce this risk. Blood tests to check neutrophils, a type of white blood cell, are needed before and during treatment.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not use Kineret if you have a known allergy to anakinra, any component of Kineret, or proteins derived from E. coli. Treatment must not be started if you have an active infection. Serious infections require prompt medical review. Kineret should be stopped if a serious infection develops during treatment for rheumatoid arthritis. For patients with NOMID or DIRA, the prescriber must weigh the risk of a disease flare if treatment is stopped against the risks of continuing it. Severe allergic reactions, including anaphylaxis and angioedema, and serious skin reactions such as DRESS can occur. If these occur, Kineret must be stopped, the reaction treated promptly, and monitoring continued until it resolves. Patients with DIRA may have a higher risk of allergic reactions, particularly during the first several weeks of treatment. Using Kineret with TNF-blocking medicines is not recommended. Live vaccines must not be given during treatment. Neutrophil counts should be checked before treatment, monthly for the first three months, then every three months for up to one year. Extra caution is needed in older people because infections are more common in this group, and in people with impaired kidney function because the risk of toxic effects may be greater. The effects of Kineret on active or chronic infections and on the development of cancer are not known. Rotate injection sites to reduce the risk of amyloid deposits at injection sites.
Using Kineret
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label KINERET (ANAKINRA) INJECTION, SOLUTION [SWEDISH ORPHAN BIOVITRUM AB (PUBL)] (DailyMed, retrieved 19 September 2026).
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