Desonide, illustration of cream tube form (not a photo of the actual pack)

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Desonide

Desonide

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About Desonide

Overview

Desonide cream is a low-potency corticosteroid for use on the skin. It is used to relieve inflammation and itching caused by skin conditions that respond to corticosteroids. It works by reducing inflammation and easing itching in the affected skin.

What it treats

- Inflammation and itching caused by skin conditions that respond to corticosteroid treatment.

Safety information

Side effects

Reported side effects of desonide cream include itching, burning, irritation, redness, pain, rash, inflamed hair follicles, pus-filled rash, sweating and swelling. Other skin reactions reported infrequently with topical corticosteroids include dryness, acne-like breakouts, rash around the mouth, heat rash, stretch marks and lighter skin colour. These reactions may occur more often when treated skin is covered with an airtight dressing or when higher-potency corticosteroids are used. Effects that warrant contacting your doctor include skin infection, allergic skin reactions and skin thinning. Increased blood sugar and abnormal liver function tests were also reported in desonide cream trials and should be discussed with your doctor.

Before taking this medicine

Do not use desonide cream if you have a history of an allergic reaction to desonide or any other ingredient in the cream.

Using Desonide

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store below 25°C with the cap closed, away from direct light and heat. Do not freeze. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label DESONIDE CREAM [ALEMBIC PHARMACEUTICALS INC.] (DailyMed, retrieved 19 September 2026).

Patient information and references

Official and supporting information to read alongside advice from your prescriber or pharmacist.

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