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Cytotec
Misopristol
$342.00
200 mcg · 6 × 60 tablets · 3 months supply
BrandBranded medicine· By Pfizer
$114.00 per month
How long a supply?
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Annual cost
$1368a year at this pack size
Prescription required
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200 mcg
FDA boxed warning
WARNINGS
CYTOTEC (MISOPROSTOL) ADMINISTRATION TO WOMEN WHO ARE PREGNANT CAN CAUSE BIRTH DEFECTS, ABORTION, PREMATURE BIRTH OR UTERINE RUPTURE.
UTERINE RUPTURE HAS BEEN REPORTED WHEN CYTOTEC WAS ADMINISTERED IN PREGNANT WOMEN TO INDUCE LABOR OR TO INDUCE ABORTION. THE RISK OF UTERINE RUPTURE INCREASES WITH ADVANCING GESTATIONAL AGES AND WITH PRIOR UTERINE SURGERY, INCLUDING CESAREAN DELIVERY (see also
PRECAUTIONS
and
LABOR AND DELIVERY).
CYTOTEC SHOULD NOT BE TAKEN BY PREGNANT WOMEN TO REDUCE THE RISK OF ULCERS INDUCED BY NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) (see
CONTRAINDICATIONS
Cytotec should not be used for reducing the risk of NSAID-induced ulcers in women of childbearing potential unless the patient is at high risk of complications from gastric ulcers associated with use of the NSAID, or is at high risk of developing gastric ulceration. In such patients, Cytotec may be prescribed if the patient
has had a negative serum pregnancy test within 2 weeks prior to beginning therapy.
is capable of complying with effective contraceptive measures.
will begin Cytotec only on the second or third day of the next normal menstrual period.
About Cytotec
Overview
Cytotec is a prescription tablet containing misoprostol, a synthetic version of prostaglandin E1. It helps reduce the risk of stomach ulcers caused by NSAIDs, including aspirin, in people at high risk of ulcers or ulcer complications. Misoprostol acts as a prostaglandin E1 analogue. Cytotec has not been shown to reduce duodenal ulcers or relieve stomach pain or discomfort associated with NSAID use.
What it treats
Reducing the risk of stomach ulcers caused by NSAIDs, including aspirin, in patients at high risk of ulcers or ulcer complications, such as older adults, people with debilitating illnesses, or those with a history of ulcers.
Safety information
FDA boxed warning
WARNINGS
CYTOTEC (MISOPROSTOL) ADMINISTRATION TO WOMEN WHO ARE PREGNANT CAN CAUSE BIRTH DEFECTS, ABORTION, PREMATURE BIRTH OR UTERINE RUPTURE.
UTERINE RUPTURE HAS BEEN REPORTED WHEN CYTOTEC WAS ADMINISTERED IN PREGNANT WOMEN TO INDUCE LABOR OR TO INDUCE ABORTION. THE RISK OF UTERINE RUPTURE INCREASES WITH ADVANCING GESTATIONAL AGES AND WITH PRIOR UTERINE SURGERY, INCLUDING CESAREAN DELIVERY (see also
PRECAUTIONS
and
LABOR AND DELIVERY).
CYTOTEC SHOULD NOT BE TAKEN BY PREGNANT WOMEN TO REDUCE THE RISK OF ULCERS INDUCED BY NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) (see
CONTRAINDICATIONS
Cytotec should not be used for reducing the risk of NSAID-induced ulcers in women of childbearing potential unless the patient is at high risk of complications from gastric ulcers associated with use of the NSAID, or is at high risk of developing gastric ulceration. In such patients, Cytotec may be prescribed if the patient
has had a negative serum pregnancy test within 2 weeks prior to beginning therapy.
is capable of complying with effective contraceptive measures.
will begin Cytotec only on the second or third day of the next normal menstrual period.
A boxed warning is the strongest warning the US Food and Drug Administration requires on a medicine label. Text is taken from the official label, with internal section references removed.
When to call your doctor
If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.
Before taking this medicine
Do not take Cytotec to reduce the risk of ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs) if you are pregnant. Do not take Cytotec if you have a history of allergy to prostaglandins.
Interactions
Cytotec may increase the effects of medicines that stimulate uterine contractions, such as oxytocin, especially if Cytotec is given less than 4 hours before oxytocin is started. Using them together is not recommended. Tell your doctor if you are receiving or are due to receive oxytocin. Cytotec has not been shown to interfere with aspirin’s benefits for rheumatoid arthritis symptoms. It has no clinically significant effect on aspirin absorption, blood levels or antiplatelet activity, or on how the body processes diclofenac or ibuprofen.
Using Cytotec
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store below 25°C in a dry place, in the original pack, away from direct light and moisture. Do not keep it in a bathroom. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label CYTOTEC (MISOPROSTOL) TABLET [PFIZER LABORATORIES DIV PFIZER INC] (DailyMed, retrieved 19 September 2026).
Patient information and references
Official and supporting information to read alongside advice from your prescriber or pharmacist.
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