Caverject Impulse, illustration of pre-filled syringe form (not a photo of the actual pack)

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Caverject Impulse

Alprostadil

Prescription required

$76.00

10MCG · 1

BrandBranded medicine· By Pfizer

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10MCG

15MCG/1ML

20MCG/ML

About Caverject Impulse

Overview

Caverject Impulse contains alprostadil, a synthetic version of a naturally occurring substance called prostaglandin E1. It is used to treat erectile dysfunction and may also be used alongside other tests to help diagnose it. It works by relaxing muscle and widening blood vessels in the penis, allowing blood to enter and stay there to produce an erection.

What it treats

• Treatment of erectile dysfunction. • Use alongside other diagnostic tests to help diagnose erectile dysfunction.

Safety information

Side effects

Penile pain is the most common side effect, reported in at least 10% of patients. Seek immediate medical help if an erection lasts longer than 4 hours. Prolonged erections and priapism have been reported. Contact your doctor if you develop a bend in the penis or signs of scarring or hardening of penile tissue (penile fibrosis). Regular checks are needed to detect these changes, and treatment must be stopped if penile angulation or cavernosal fibrosis develops. Other risks include low blood pressure and bleeding at the injection site, particularly if you take anticoagulants such as warfarin or heparin. Apply pressure to the injection site with an alcohol swab or sterile gauze for 5 minutes. Needle breakage has also been reported. Proper instruction in handling and injection technique may reduce this risk.

When to call your doctor

• Seek immediate medical attention if an erection lasts longer than 4 hours.

If symptoms are severe or getting worse quickly, seek emergency care rather than waiting.

Before taking this medicine

Do not use Caverject Impulse if you are allergic to alprostadil, have a penile implant, or have a condition that increases the risk of priapism (a prolonged erection), such as sickle cell anemia or sickle cell trait, multiple myeloma, or leukemia. It must not be used to treat erectile dysfunction in men with penile deformity, angulation, scarring of the erectile tissue, or Peyronie’s disease. Avoid use if you have known leakage from the veins in the penis (cavernosal venous leakage), as this can increase the risk of low blood pressure. Tell your prescriber if you take anticoagulants such as warfarin or heparin, which can increase bleeding at the injection site. If bleeding occurs, press the site with an alcohol swab or sterile gauze for 5 minutes. Underlying treatable causes of erectile dysfunction should be assessed and treated before starting therapy, including conditions that may pose cardiovascular risks. Combining Caverject Impulse with other medicines injected into the penis that affect blood vessels is not recommended. Seek immediate medical help for an erection lasting longer than 4 hours. Regular follow-up is needed to check for penile scarring; treatment should be stopped if penile angulation or scarring of the erectile tissue develops. Proper handling and injection training are important because needle breakage has been reported. Caverject Impulse is not indicated for newborns or infants. Its benzyl alcohol preservative can cause serious or fatal reactions in newborns and low-birth-weight infants.

Interactions

Interactions between alprostadil and other medicines taken by mouth or injected into the penis have not been formally studied. Discuss these medicines with your doctor.

Using Caverject Impulse

Dosing

Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.

Storage

Store in the original carton to protect it from light. Check the pack for whether it must be refrigerated before first use. Keep all medicines out of the sight and reach of children.

Clinical information on this page is summarised from the US FDA label CAVERJECT IMPULSE (ALPROSTADIL) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [PHARMACIA & UPJOHN COMPANY LLC] (DailyMed, retrieved 19 September 2026).

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