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ABRYSVO
Rsv Prefusion F Protein (bivalent Rsvpref, Stabilized Pre‑fusion F Antigens From Rsv A And B)
$396.00
120MCG · 1 vial
BrandBranded medicine· By Pfizer
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About ABRYSVO
Overview
ABRYSVO is a vaccine containing stabilized prefusion F proteins from respiratory syncytial virus (RSV) types A and B. It is used to help prevent RSV-related lower respiratory tract disease in adults aged 60 and older and adults aged 18–59 who are at increased risk. It is also used in pregnant individuals at 32–36 weeks of pregnancy to help protect infants from birth through 6 months against RSV-related lower respiratory tract disease, including severe disease. It works by triggering an immune response against RSV; antibodies produced during pregnancy can cross the placenta to protect the infant.
What it treats
- Prevention of RSV-related lower respiratory tract disease, including severe disease, in infants from birth through 6 months of age through vaccination during pregnancy at 32–36 weeks. - Prevention of RSV-related lower respiratory tract disease in adults aged 60 years and older. - Prevention of RSV-related lower respiratory tract disease in adults aged 18–59 years who are at increased risk.
Safety information
Side effects
Common side effects vary by group: • In pregnant individuals: injection-site pain, headache, muscle pain and nausea. • In adults aged 60 and older: fatigue, headache, injection-site pain and muscle pain. • In adults aged 18–59 with chronic medical conditions: injection-site pain, muscle pain, joint pain and nausea. Serious risks include Guillain-Barré syndrome. A study conducted after ABRYSVO became available suggests an increased risk during the 42 days after vaccination. Contact a doctor promptly if you suspect this condition. The label also warns of a potential risk of preterm birth when ABRYSVO is given before 32 weeks of pregnancy. Contact a doctor promptly if you have concerns about possible preterm birth.
Before taking this medicine
ABRYSVO must not be given to anyone who has had a severe allergic reaction, including anaphylaxis, to any of its components. A study conducted after marketing suggests an increased risk of Guillain-Barré syndrome during the 42 days after vaccination. In pregnancy, ABRYSVO should only be given at 32 through 36 weeks of gestation because of the potential risk of preterm birth if given before 32 weeks.
Interactions
Tell your doctor if you are due to receive a Tdap vaccine (tetanus, diphtheria and whooping cough). In a study in non-pregnant women, giving ABRYSVO and Tdap together raised no safety concerns. Immune responses to RSV, diphtheria and tetanus were comparable to separate administration, but antibody levels against whooping cough components were lower than when Tdap was given alone. Giving ABRYSVO and Tdap together during pregnancy has not been studied.
Using ABRYSVO
Dosing
Dosing is set by your prescriber. Each health care professional may prescribe medication differently according to a patient's medical history and condition, so follow the directions on your prescription label and speak to your doctor or pharmacist before changing anything.
Storage
Store in the original carton below 25°C, protected from light, unless the pack states refrigeration. Do not freeze. Keep all medicines out of the sight and reach of children.
Clinical information on this page is summarised from the US FDA label ABRYSVO (RESPIRATORY SYNCYTIAL VIRUS VACCINE) KIT ABRYSVO (RESPIRATORY SYNCYTIAL VIRUS VACCINE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [PFIZER LABORATORIES DIV PFIZER INC] (DailyMed, retrieved 19 September 2026).
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